Delivery in pregnant women infected with SARS-CoV-2: A fast review.
Int J Gynaecol Obstet
; 150(1): 41-46, 2020 Jul.
Article
in English
| MEDLINE | ID: covidwho-1196384
ABSTRACT
BACKGROUND:
Few case reports and clinical series exist on pregnant women infected with SARS-CoV-2 who delivered.OBJECTIVE:
To review the available information on mode of delivery, vertical/peripartum transmission, and neonatal outcome in pregnant women infected with SARS-CoV-2. SEARCH STRATEGY Combination of the following key words COVID-19, SARS-CoV-2, and pregnancy in Embase and PubMed databases. SELECTION CRITERIA Papers reporting cases of women infected with SARS-CoV-2 who delivered. DATA COLLECTION ANDANALYSIS:
The following was extracted author; country; number of women; study design; gestational age at delivery; selected clinical maternal data; mode of delivery; selected neonatal outcomes. MAINRESULTS:
In the 13 studies included, vaginal delivery was reported in 6 cases (9.4%; 95% CI, 3.5-19.3). Indication for cesarean delivery was worsening of maternal conditions in 31 cases (48.4%; 95% CI, 35.8-61.3). Two newborns testing positive for SARS-CoV-2 by real-time RT-PCR assay were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated but the RT-PCR test was negative.CONCLUSIONS:
The rate of vertical or peripartum transmission of SARS-CoV-2 is low, if any, for cesarean delivery; no data are available for vaginal delivery. Low frequency of spontaneous preterm birth and general favorable immediate neonatal outcome are reassuring.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Pregnancy Complications, Infectious
/
Coronavirus Infections
/
Infectious Disease Transmission, Vertical
/
Delivery, Obstetric
/
Betacoronavirus
Type of study:
Prognostic study
/
Reviews
Limits:
Adult
/
Female
/
Humans
/
Infant, Newborn
/
Pregnancy
Language:
English
Journal:
Int J Gynaecol Obstet
Year:
2020
Document Type:
Article
Affiliation country:
Ijgo.13166
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