Passive immunity in newborn from SARS-CoV-2-infected mother.
J Med Virol
; 93(3): 1810-1813, 2021 03.
Article
in English
| MEDLINE | ID: covidwho-1196504
ABSTRACT
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vertical transmission is an open issue. Recent reports call into question in utero or peripartum viral transmission to the offspring. Few data are available on immunoglobulin G (IgG) and/or IgM in newborns. Insufficient evidence is available regarding passive immunity in neonates born from SARS-CoV-2 infected women. We report a case of a neonate showing the presence of blood specific IgG and the absence of IgM and negative nasopharyngeal swab. He was born from an asymptomatic SARS-CoV-2-infected mother with positive IgG and IgM. The transplacental passage of specific IgG antibodies from the affected mother to the unaffected fetus highlights neonatal passive immunity.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Infectious Disease Transmission, Vertical
/
SARS-CoV-2
/
COVID-19
/
Immunity, Maternally-Acquired
/
Antibodies, Viral
Type of study:
Diagnostic study
Limits:
Adult
/
Female
/
Humans
/
Male
/
Infant, Newborn
/
Pregnancy
Language:
English
Journal:
J Med Virol
Year:
2021
Document Type:
Article
Affiliation country:
Jmv.26609
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