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Outcomes of acute respiratory distress syndrome in COVID-19 patients compared to the general population: a systematic review and meta-analysis.
Dmytriw, Adam A; Chibbar, Richa; Chen, Petty Pin Yu; Traynor, Michael D; Kim, Dong Wook; Bruno, Fernando P; Cheung, Christopher C; Pareek, Anuj; Chou, Andrew Chia Chen; Graham, Jeffrey; Dibas, Mahmoud; Paranjape, Geeta; Reierson, Natalie L; Kamrowski, Shelby; Rozowsky, Jacob; Barrett, Averi; Schmidt, Megan; Shahani, Disha; Cowie, Kathryn; Davis, Amber R; Abdelmegeed, Mohamed; Touchette, Jillienne C; Kallmes, Kevin M; Pederson, John M; Keesari, Praneeth Reddy.
  • Dmytriw AA; Neuroradiology & Neurointervention Service, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Chibbar R; Department of Medicine, Lakeridge Health, Oshawa, Canada.
  • Chen PPY; ASUS AICS Department, Ministry of Health Holdings Pte Ltd, Singapore.
  • Traynor MD; Department of Surgery, Mayo Clinic, Rochester, MN, USA.
  • Kim DW; Department of Epidemiology and Case Management Cheongju, Korea Disease Control and Prevention Agency, Cheongju, South Korea.
  • Bruno FP; Department of Anatomy, Touro College of Osteopathic Medicine, Middletown, MN, USA.
  • Cheung CC; Department of Public Health, Division of Epidemiology, School of Health Sciences and Practice, New York Medical College, Valhalla, NY, USA.
  • Pareek A; Division of Cardiology, University of British Columbia, Vancouver, Canada.
  • Chou ACC; Department of Radiology, Stanford University, Stanford, CA, USA.
  • Graham J; Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
  • Dibas M; Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.
  • Paranjape G; Sulaiman Al Rajhi University, College of Medicine, Saudi Arabia.
  • Reierson NL; Research Department, Superior Medical Experts, St. Paul, MN, USA.
  • Kamrowski S; Research Department, Nested Knowledge, St. Paul, MN, USA.
  • Rozowsky J; Research Department, Nested Knowledge, St. Paul, MN, USA.
  • Barrett A; Research Department, Nested Knowledge, St. Paul, MN, USA.
  • Schmidt M; Research Department, Nested Knowledge, St. Paul, MN, USA.
  • Shahani D; Research Department, Nested Knowledge, St. Paul, MN, USA.
  • Cowie K; Research Department, Nested Knowledge, St. Paul, MN, USA.
  • Davis AR; Research Department, Nested Knowledge, St. Paul, MN, USA.
  • Abdelmegeed M; Research Department, Superior Medical Experts, St. Paul, MN, USA.
  • Touchette JC; Research Department, Superior Medical Experts, St. Paul, MN, USA.
  • Kallmes KM; Research Department, Superior Medical Experts, St. Paul, MN, USA.
  • Pederson JM; Research Department, Nested Knowledge, St. Paul, MN, USA.
  • Keesari PR; Research Department, Superior Medical Experts, St. Paul, MN, USA.
Expert Rev Respir Med ; 15(10): 1347-1354, 2021 10.
Article in English | MEDLINE | ID: covidwho-1196938
Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
2. Respiratory Distress Syndrom PROCESS_OF C0030705
Subject
Respiratory Distress Syndrom
Predicate
PROCESS_OF
Object
C0030705
3. COVID-19 CAUSES Respiratory Distress Syndrom
Subject
COVID-19
Predicate
CAUSES
Object
Respiratory Distress Syndrom
4. Respiratory Distress Syndrom NEG_COEXISTS_WITH C5203670
Subject
Respiratory Distress Syndrom
Predicate
NEG_COEXISTS_WITH
Object
C5203670
5. Respiratory Distress Syndrom PROCESS_OF C0683971
Subject
Respiratory Distress Syndrom
Predicate
PROCESS_OF
Object
C0683971
6. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
7. Respiratory Distress Syndrome, Adult PROCESS_OF Patients
Subject
Respiratory Distress Syndrome, Adult
Predicate
PROCESS_OF
Object
Patients
8. COVID-19 CAUSES Respiratory Distress Syndrome, Adult
Subject
COVID-19
Predicate
CAUSES
Object
Respiratory Distress Syndrome, Adult
9. Respiratory Distress Syndrome, Adult NEG_COEXISTS_WITH COVID-19
Subject
Respiratory Distress Syndrome, Adult
Predicate
NEG_COEXISTS_WITH
Object
COVID-19
10. Respiratory Distress Syndrome, Adult PROCESS_OF General Population
Subject
Respiratory Distress Syndrome, Adult
Predicate
PROCESS_OF
Object
General Population
ABSTRACT

INTRODUCTION:

Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) often leads to mortality. Outcomes of patients with COVID-19-related ARDS compared to ARDS unrelated to COVID-19 is not well characterized. AREAS COVERED We performed a systematic review of PubMed, Scopus, and MedRxiv 11/1/2019 to 3/1/2021, including studies comparing outcomes in COVID-19-related ARDS (COVID-19 group) and ARDS unrelated to COVID-19 (ARDS group). Outcomes investigated were duration of mechanical ventilation-free days, intensive care unit (ICU) length-of-stay (LOS), hospital LOS, and mortality. Random effects models were fit for each outcome measure. Effect sizes were reported as pooled median differences of medians (MDMs), mean differences (MDs), or odds ratios (ORs). EXPERT OPINION Ten studies with 2,281 patients met inclusion criteria (COVID-19 861 [37.7%], ARDS 1420 [62.3%]). There were no significant differences between the COVID-19 and ARDS groups for median number of mechanical ventilator-free days (MDM -7.0 [95% CI -14.8; 0.7], p = 0.075), ICU LOS (MD 3.1 [95% CI -5.9; 12.1], p = 0.501), hospital LOS (MD 2.5 [95% CI -5.6; 10.7], p = 0.542), or all-cause mortality (OR 1.25 [95% CI 0.78; 1.99], p = 0.361). Compared to the general ARDS population, results did not suggest worse outcomes in COVID-19-related ARDS.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / COVID-19 Type of study: Diagnostic study / Prognostic study / Randomized controlled trials / Reviews / Systematic review Limits: Humans Language: English Journal: Expert Rev Respir Med Year: 2021 Document Type: Article Affiliation country: 17476348.2021.1920927

Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / COVID-19 Type of study: Diagnostic study / Prognostic study / Randomized controlled trials / Reviews / Systematic review Limits: Humans Language: English Journal: Expert Rev Respir Med Year: 2021 Document Type: Article Affiliation country: 17476348.2021.1920927