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Rehabilitation of Patients with Platypnea-Orthodeoxia Syndrome in COVID-19 Pneumonia: Two Case Reports.
Tham, Shuen-Loong; Ong, Poo Lee; Lee, Audrey Jia Yi; Tay, Matthew Rong Jie.
  • Tham SL; Rehabilitation Medicine Department, Tan Tock Seng Hospital, Singapore.
  • Ong PL; Rehabilitation Medicine Department, Tan Tock Seng Hospital, Singapore.
  • Lee AJY; Physiotherapy Department, Tan Tock Seng Hospital, Singapore.
  • Tay MRJ; Rehabilitation Medicine Department, Tan Tock Seng Hospital, Singapore.
J Rehabil Med Clin Commun ; 3: 1000044, 2020.
Article in English | MEDLINE | ID: covidwho-1197496
Semantic information from SemMedBD (by NLM)
1. Syndrome COEXISTS_WITH Pneumonia caused by SARS-CoV-2
Subject
Syndrome
Predicate
COEXISTS_WITH
Object
Pneumonia caused by SARS-CoV-2
2. Syndrome PROCESS_OF Patients
Subject
Syndrome
Predicate
PROCESS_OF
Object
Patients
3. Arteries LOCATION_OF Oxygen saturation below reference range
Subject
Arteries
Predicate
LOCATION_OF
Object
Oxygen saturation below reference range
4. Dyspnea ASSOCIATED_WITH Syndrome
Subject
Dyspnea
Predicate
ASSOCIATED_WITH
Object
Syndrome
5. Pneumonia caused by SARS-CoV-2 PROCESS_OF Patients
Subject
Pneumonia caused by SARS-CoV-2
Predicate
PROCESS_OF
Object
Patients
6. Hypoxemia PROCESS_OF Patients
Subject
Hypoxemia
Predicate
PROCESS_OF
Object
Patients
7. Mechanical ventilation COEXISTS_WITH intensive care
Subject
Mechanical ventilation
Predicate
COEXISTS_WITH
Object
intensive care
8. Medical procedure on respiratory tract TREATS Syndrome
Subject
Medical procedure on respiratory tract
Predicate
TREATS
Object
Syndrome
9. Syndrome COEXISTS_WITH Pneumonia caused by SARS-CoV-2
Subject
Syndrome
Predicate
COEXISTS_WITH
Object
Pneumonia caused by SARS-CoV-2
10. Syndrome PROCESS_OF Patients
Subject
Syndrome
Predicate
PROCESS_OF
Object
Patients
11. Arteries LOCATION_OF Oxygen saturation below reference range
Subject
Arteries
Predicate
LOCATION_OF
Object
Oxygen saturation below reference range
12. Dyspnea ASSOCIATED_WITH Syndrome
Subject
Dyspnea
Predicate
ASSOCIATED_WITH
Object
Syndrome
13. Pneumonia caused by SARS-CoV-2 PROCESS_OF Patients
Subject
Pneumonia caused by SARS-CoV-2
Predicate
PROCESS_OF
Object
Patients
14. Hypoxemia PROCESS_OF Patients
Subject
Hypoxemia
Predicate
PROCESS_OF
Object
Patients
15. Mechanical ventilation COEXISTS_WITH intensive care
Subject
Mechanical ventilation
Predicate
COEXISTS_WITH
Object
intensive care
16. Medical procedure on respiratory tract TREATS Syndrome
Subject
Medical procedure on respiratory tract
Predicate
TREATS
Object
Syndrome
ABSTRACT
Platypnea-orthodeoxia syndrome, characterized by dyspnoea and arterial desaturation while upright, is a rare complication of acute respiratory distress syndrome. We report here 2 patients with COVID-19 pneumonia, who were diagnosed with platypnea-orthodeoxia syndrome during commencement of rehabilitation, 18 and 9 days respectively after admission to the intensive care unit. Both patients presented with normocapnic hypoxaemia. One patient required mechanical ventilation with supplemental oxygen during intensive care, while the other required high-flow nasal oxygen therapy. The manifestations of platypnea-orthodeoxia syndrome were most prominent during physiotherapy, when verticalization was attempted, and hindered further mobilization out of bed, including ambulation. This report describes the clinical manifestations of platypnea-orthodeoxia syndrome and the rehabilitative strategies carried out for these 2 patients. The platypnea-orthodeoxia syndrome in these patients resolved after 65 and 22 days respectively from the day of detection. This report highlights this potentially under-recognized phenomenon, which may be unmasked during rehabilitation of patients with COVID-19 pneumonia. Good functional outcomes were achieved with a combination of verticalization training with supplemental oxygen support, respiratory techniques training and progressive endurance and resistance training, whilst awaiting resolution of the platypneaorthodeoxia syndrome.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Language: English Journal: J Rehabil Med Clin Commun Year: 2020 Document Type: Article Affiliation country: 20030711-1000044

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Language: English Journal: J Rehabil Med Clin Commun Year: 2020 Document Type: Article Affiliation country: 20030711-1000044