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POS-510 Analysis and monitoring of the spread of SARS-COV-2 infection among patients of Nephrology-Dialysis Units in Piedmont and Valle d'Aosta
Kidney International Reports ; 6(4):S221, 2021.
Article in English | EMBASE | ID: covidwho-1198727
ABSTRACT

Introduction:

The ongoing SARS-COV-2 pandemic hit the world’s population since the first trimester of 2020. Since the beginning it has been clear that the elderly and chronic patients were at greater risk ofmorbidity and mortality. The aim of the study was to monitor the spread and outcomes amongpatients in kidney replacement therapy treated in Nephrology-Dialysis units in Piedmont and Valled’Aosta Regions, North-West Italy.

Methods:

A web platform accessible by Dialysis coordinators across the first and second wave of the pandemic is still being used to collect and regularly update demographic and clinical data of patients. We present preliminary results on cumulative incidence, risk estimates and measures of association. Data were analyzed using SPSS version 19 and Wizard 1.9.47 for Mac.

Results:

An overall of 599 cases has been monitored since March 2020 till November 2020. The cumulative incidence is 10% compared to 3,3% of the general population. A higher cumulative incidence has been observed among Hemodialysis patients (14%), while in peritoneal dialysis patients and transplant receivers’ sub-groups it is 5,3% and 6,6%, respectively. Compared to the general population, among dialysis patients, cumulative incidence grew at a slower rate in the first than in the second wave of pandemic (incidence rate ratio of 1,65 for patients compared to 5,9 for the rest of the population). A higher fatality risk is observed among dialysis patients and transplant receivers (17% and11%, respectively) compared to that of the general population of 3,7%. Fatality is associated with age and cardiovascular diseases in both groups.

Conclusions:

The study of an overall population of 599 showed a higher susceptibility to SARS-COV-2 infection and worse outcomes compared to the general population. We observed increased risks for hemodialysis patients, who are older on average and more exposed to in-hospital infections. No conflict of interest

Full text: Available Collection: Databases of international organizations Database: EMBASE Language: English Journal: Kidney International Reports Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Language: English Journal: Kidney International Reports Year: 2021 Document Type: Article