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Abstinence Among Alcohol Use Disorder Patients During the COVID-19 Pandemic: Insights From Spain.
Barrio, Pablo; Baldaquí, Nuria; Andreu, Magalí; Kilian, Carolin; Rehm, Jürgen; Gual, Antoni; Manthey, Jakob.
  • Barrio P; Grup Recerca Addiccions Clínic (GRAC-GRE), Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic Barcelona, Barcelona, Spain.
  • Baldaquí N; Grup Recerca Addiccions Clínic (GRAC-GRE), Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic Barcelona, Barcelona, Spain.
  • Andreu M; Grup Recerca Addiccions Clínic (GRAC-GRE), Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic Barcelona, Barcelona, Spain.
  • Kilian C; Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
  • Rehm J; Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
  • Gual A; Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, Toronto, Ontario, Canada.
  • Manthey J; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Alcohol Clin Exp Res ; 45(4): 802-807, 2021 04.
Article in English | MEDLINE | ID: covidwho-1199627
ABSTRACT

BACKGROUND:

Patients with alcohol use disorder (AUD) are likely to suffer disproportionate harms related to the COVID-19 pandemic and related policy measures. While many surveys have been conducted, most are focused on drinking changes in the general population and validation with biological markers is lacking.

METHOD:

We performed a retrospective cohort study among patients with AUD attending a urine drug screening program. With mixed-effects logistic regression models, we assessed the probability of screening positive for ethyl glucuronide according to patients' main clinical characteristics and time of analysis (either prior to or after a lockdown was implemented in Spain).

RESULTS:

A total of 362 patients provided 2,040 urine samples (1,295 prior to lockdown, 745 during lockdown). The mean age of participants was 52.0 years (SD 12.6), and 69.2% were men. Of the 43% of patients tested for other drugs 22% screened positive. After adjusting for all covariates, the odds of screening positive for ethyl glucuronide during lockdown almost doubled (OR = 1.99, 95% CI 1.20 to 3.33, p = 0.008). Other significant covariates included testing positive for other drugs (OR = 10.79, 95% CI 4.60 to 26.97) and length of treatment (OR = 0.59, 95% CI 0.47 to 0.74).

CONCLUSIONS:

Our data support an association between the lockdown due to COVID-19 and increased alcohol use in patients with AUD. Thus, addiction healthcare systems could face significant challenges ahead. In light of these findings, it is essential to evaluate prospectively how patients with AUD are affected by the pandemic and how health systems respond to their needs.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Quarantine / Alcoholism / Alcohol Abstinence / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Qualitative research Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Europa Language: English Journal: Alcohol Clin Exp Res Year: 2021 Document Type: Article Affiliation country: Acer.14555

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Quarantine / Alcoholism / Alcohol Abstinence / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Qualitative research Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Europa Language: English Journal: Alcohol Clin Exp Res Year: 2021 Document Type: Article Affiliation country: Acer.14555