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Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology.
Nazy, Ishac; Sachs, Ulrich J; Arnold, Donald M; McKenzie, Steven E; Choi, Phil; Althaus, Karina; Ahlen, Maria Therese; Sharma, Ruchika; Grace, Rachael F; Bakchoul, Tamam.
  • Nazy I; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
  • Sachs UJ; McMaster Centre for Transfusion Research, Hamilton, ON, Canada.
  • Arnold DM; Department of Thrombosis and Haemostasis, Giessen University Hospital, Giessen, Germany.
  • McKenzie SE; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
  • Choi P; McMaster Centre for Transfusion Research, Hamilton, ON, Canada.
  • Althaus K; Cardeza Foundation for Hematological Research, Thomas Jefferson University, Philadelphia, PA, USA.
  • Ahlen MT; Haematology Department, The Canberra Hospital, Canberra, ACT, Australia.
  • Sharma R; John Curtin School of Medical Research, ANU, Canberra, ACT, Australia.
  • Grace RF; Transfusion Medicine, Medical Faculty of Tuebingen, University of Tuebingen, Tuebingen, Germany.
  • Bakchoul T; Centre for Clinical Transfusion Medicine Tuebingen ZKT gGmbH, Tuebingen, Germany.
J Thromb Haemost ; 19(6): 1585-1588, 2021 06.
Article in English | MEDLINE | ID: covidwho-1247252
ABSTRACT
Vaccine administration is under way worldwide to combat the current COVID-19 pandemic. The newly developed vaccines are highly effective with minimal adverse effects. Recently, the AstraZeneca ChadOx1 nCov-19 vaccine has raised public alarm with concerns regarding the rare, but serious, development of thrombotic events, now known as vaccine-induced immune thrombotic thrombocytopenia (VITT). These thrombotic events appear similar to heparin-induced thrombocytopenia, both clinically and pathologically. In this manuscript, the ISTH SSC Subcommittee on Platelet Immunology outlines guidelines on how to recognize, diagnose and manage patients with VITT.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Thromb Haemost Journal subject: Hematology Year: 2021 Document Type: Article Affiliation country: Jth.15341

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Thromb Haemost Journal subject: Hematology Year: 2021 Document Type: Article Affiliation country: Jth.15341