Severe Inflammation, Acute Kidney Injury, and Drug-Drug Interaction: Triple Penalty for Prolonged Elimination of Apixaban in Patients With Coronavirus Disease 2019: A Grand Round.
Ther Drug Monit
; 43(4): 455-458, 2021 08 01.
Article
in English
| MEDLINE | ID: covidwho-1305444
ABSTRACT
ABSTRACT In this article, we present a case of apixaban elimination prolonged by 450% in a patient with coronavirus disease 2019 because of multiple conditions, including drug-drug interaction, severe inflammation, and acute kidney injury. Therapeutic drug monitoring was used to explain unusual routine coagulation assays. This grand round highlights the importance of dialog between the clinician and a therapeutic drug monitoring consultant for optimal patient care.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pyrazoles
/
Pyridones
/
Drug Monitoring
/
Teaching Rounds
/
Acute Kidney Injury
/
Renal Elimination
/
COVID-19
Type of study:
Case report
/
Observational study
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Ther Drug Monit
Year:
2021
Document Type:
Article
Affiliation country:
FTD.0000000000000899
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