Your browser doesn't support javascript.
COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world?
Revannavar, Shweta Mallikarjun; P S, Supriya; Samaga, Laxminarayana; V K, Vineeth.
  • Revannavar SM; General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India shweta.connect2@gmail.com.
  • P S S; General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.
  • Samaga L; General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.
  • V K V; General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.
BMJ Case Rep ; 14(4)2021 Apr 27.
Article in English | MEDLINE | ID: covidwho-1206018
Semantic information from SemMedBD (by NLM)
1. COVID-19 CAUSES Mucormycosis
Subject
COVID-19
Predicate
CAUSES
Object
Mucormycosis
2. Mucormycosis PROCESS_OF Patients
Subject
Mucormycosis
Predicate
PROCESS_OF
Object
Patients
3. Blepharoptosis PROCESS_OF Middle-aged women
Subject
Blepharoptosis
Predicate
PROCESS_OF
Object
Middle-aged women
4. Facial Pain PROCESS_OF Middle-aged women
Subject
Facial Pain
Predicate
PROCESS_OF
Object
Middle-aged women
5. Fever PROCESS_OF Middle-aged women
Subject
Fever
Predicate
PROCESS_OF
Object
Middle-aged women
6. Diabetes PROCESS_OF Middle-aged women
Subject
Diabetes
Predicate
PROCESS_OF
Object
Middle-aged women
7. Eye LOCATION_OF Total ophthalmoplegia
Subject
Eye
Predicate
LOCATION_OF
Object
Total ophthalmoplegia
8. Left occipital lobe structure LOCATION_OF Acute infarct
Subject
Left occipital lobe structure
Predicate
LOCATION_OF
Object
Acute infarct
9. Nuclear magnetic resonance imaging brain DIAGNOSES Pansinusitis
Subject
Nuclear magnetic resonance imaging brain
Predicate
DIAGNOSES
Object
Pansinusitis
10. CAT scan of brain DIAGNOSES Sinusitis
Subject
CAT scan of brain
Predicate
DIAGNOSES
Object
Sinusitis
11. CAT scan of brain DIAGNOSES Mucosal thickening
Subject
CAT scan of brain
Predicate
DIAGNOSES
Object
Mucosal thickening
12. Diabetes PROCESS_OF Patients
Subject
Diabetes
Predicate
PROCESS_OF
Object
Patients
13. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
14. Brain Infarction PROCESS_OF Patients
Subject
Brain Infarction
Predicate
PROCESS_OF
Object
Patients
15. Rapidly progressive COEXISTS_WITH Mucormycosis
Subject
Rapidly progressive
Predicate
COEXISTS_WITH
Object
Mucormycosis
16. COVID-19 CAUSES Mucormycosis
Subject
COVID-19
Predicate
CAUSES
Object
Mucormycosis
17. Mucormycosis PROCESS_OF Patients
Subject
Mucormycosis
Predicate
PROCESS_OF
Object
Patients
18. Blepharoptosis PROCESS_OF Middle-aged women
Subject
Blepharoptosis
Predicate
PROCESS_OF
Object
Middle-aged women
19. Facial Pain PROCESS_OF Middle-aged women
Subject
Facial Pain
Predicate
PROCESS_OF
Object
Middle-aged women
20. Fever PROCESS_OF Middle-aged women
Subject
Fever
Predicate
PROCESS_OF
Object
Middle-aged women
21. Diabetes PROCESS_OF Middle-aged women
Subject
Diabetes
Predicate
PROCESS_OF
Object
Middle-aged women
22. Eye LOCATION_OF Total ophthalmoplegia
Subject
Eye
Predicate
LOCATION_OF
Object
Total ophthalmoplegia
23. Left occipital lobe structure LOCATION_OF Acute infarct
Subject
Left occipital lobe structure
Predicate
LOCATION_OF
Object
Acute infarct
24. Nuclear magnetic resonance imaging brain DIAGNOSES Pansinusitis
Subject
Nuclear magnetic resonance imaging brain
Predicate
DIAGNOSES
Object
Pansinusitis
25. CAT scan of brain DIAGNOSES Sinusitis
Subject
CAT scan of brain
Predicate
DIAGNOSES
Object
Sinusitis
26. CAT scan of brain DIAGNOSES Mucosal thickening
Subject
CAT scan of brain
Predicate
DIAGNOSES
Object
Mucosal thickening
27. Diabetes PROCESS_OF Patients
Subject
Diabetes
Predicate
PROCESS_OF
Object
Patients
28. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
29. Brain Infarction PROCESS_OF Patients
Subject
Brain Infarction
Predicate
PROCESS_OF
Object
Patients
30. Rapidly progressive COEXISTS_WITH Mucormycosis
Subject
Rapidly progressive
Predicate
COEXISTS_WITH
Object
Mucormycosis
ABSTRACT
A middle-aged woman with diabetes presented with left-sided facial pain, complete ptosis and fever of short duration. On presentation, she had hyperglycaemia without ketosis. There was total ophthalmoplegia of the left eye with a visual acuity of 6/36. She incidentally tested positive for COVID-19. CT paranasal sinus and MRI brain revealed left-sided pansinusitis with acute infarct in the left parieto-occipital region without angioinvasion. An emergency functional endoscopic sinus procedure was done, which confirmed mucormycosis on histopathological examination. After 1 week of conventional amphotericin B and antibiotics, repeat CT brain showed improvement in mucosal thickening and sinusitis. This case is a rare presentation of mucormycosis associated with rapid progression to orbital apex syndrome with brain infarction in a patient with non-ketotic diabetes and COVID-19. Early diagnosis and treatment are essential to prevent further end-organ damage. It is also interesting that there was no angioinvasion and transient periarterial inflammation was attributed to brain infarction.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Orbital Diseases / Paranasal Sinus Diseases / Blepharoptosis / Ophthalmoplegia / Diabetes Complications / COVID-19 / Mucormycosis Type of study: Etiology study / Screening study Topics: Long Covid Limits: Female / Humans / Middle aged Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2021-241663

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Orbital Diseases / Paranasal Sinus Diseases / Blepharoptosis / Ophthalmoplegia / Diabetes Complications / COVID-19 / Mucormycosis Type of study: Etiology study / Screening study Topics: Long Covid Limits: Female / Humans / Middle aged Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2021-241663