Comparative evaluation of liver function with different grades of lung involvement in covid 19 patients
Annals of the Romanian Society for Cell Biology
; 25(3):3040-3055, 2021.
Article
in English
| Scopus | ID: covidwho-1208002
ABSTRACT
Background:
The coronavirus disease 2019 (COVID-19) outbreak is the global pandemic causes severe acute respiratory syndrome, affects the liver in the earlier stages⁵. In our biochemistry laboratory we observed most of the covid-19 patients have deranged liver function tests commonly mixed type. Thus the main aim of our study was to analyse the association of LFT with lung involvement in symptomatic covid-19 patients with or without comorbidities.Method:
This study is a retrospective cross sectional study, where we collected 1000 biochemical data of RT-PCR confirmed COVID-19 cases with positive CT-chest reports at the time of admission, before starting the treatment and analyzed the biochemistry data in 2 different forms. One is comparing the data of covid-19 positive cases with comorbidity to no comorbidity. Another form, the cases were classified into 4 grades based on the CT-chest, and analyzed the relationship between CT-Chest and liver function parameters.Results:
The data of 1000 cases were compared statistically. It showed a significant number of patients with COVID-19, had abnormal liver function at the earlier state on infection. 90% of the cases have at least one abnormal liver function tests.Patients having >50% lung involvement have increased enzyme levels and decreased total protein and albumin levels, when compared with those having <50% lung involvementConclusion:
In COVID-19 patients, apart from the lung involvement, extra pulmonary manifestations are also common. Liver is the most commonly affected along with lung at earlier stages. © 2021, Universitatea de Vest Vasile Goldis din Arad. All rights reserved.
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Collection:
Databases of international organizations
Database:
Scopus
Type of study:
Experimental Studies
Language:
English
Journal:
Annals of the Romanian Society for Cell Biology
Year:
2021
Document Type:
Article
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