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The breadth of concomitant virological features in a family cluster outbreak of COVID-19 pneumonia.
Lei, Guanglin; Meng, Fanping; Wang, Cheng; Yan, Jin; Sun, Fang; Shi, Lei; Li, Wengang; Luan, Junqing; Wang, Siyu; Yang, Penghui.
  • Lei G; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
  • Meng F; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
  • Wang C; Department of Orthopedics, First Medical Center, Chinese PLA General Hospital, Beijing, China.
  • Yan J; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
  • Sun F; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
  • Shi L; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
  • Li W; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
  • Luan J; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
  • Wang S; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
  • Yang P; Department of Hepatobiliary Surgery, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, P. R. China.
J Med Virol ; 93(9): 5635-5637, 2021 09.
Article in English | MEDLINE | ID: covidwho-1208550
ABSTRACT
An outbreak of a novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had emerged in 2019 and rapidly posed a global epidemic. Here, we report the breadth of concomitant virological features of a family cluster with COVID-19. The period of virus shedding is significantly different between upper respiratory and feces samples. Even the SARS-CoV-2 virus titers were undetectable in feces, it could be positive again soon and likely related to fluctuated inflammation levels (interleukin-6, etc.) and lowered immune responses (CD4 + T lymphocyte, etc.). Our findings expand the novel understanding of the breadth of concomitant virological features during a non-severe family cluster of COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Shedding / Feces / SARS-CoV-2 / COVID-19 Type of study: Case report Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Shedding / Feces / SARS-CoV-2 / COVID-19 Type of study: Case report Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2021 Document Type: Article