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Chitin and chitosan as tools to combat COVID-19: A triple approach.
Safarzadeh, Mehrnoush; Sadeghi, Sahar; Azizi, Mahdieh; Rastegari-Pouyani, Mohsen; Pouriran, Ramin; Haji Molla Hoseini, Mostafa.
  • Safarzadeh M; Student Research Committee, Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Sadeghi S; Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Azizi M; Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Rastegari-Pouyani M; Student Research Committee, Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Pouriran R; School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Haji Molla Hoseini M; Medical Nanotechnology and Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: m.mollahoseini@sbmu.ac.ir.
Int J Biol Macromol ; 183: 235-244, 2021 Jul 31.
Article in English | MEDLINE | ID: covidwho-1208614
ABSTRACT
The progressive and fatal outbreak of the newly emerged coronavirus, SARS-CoV-2, necessitates rigorous collaboration of all health care systems and researchers from all around the world to bring such a devastating pandemic under control. As there is so far no officially approved drug or ideal vaccine for this disease, investigations on this infectious disease are actively pursued. Chitin and chitosan have shown promising results against viral infections. In this review, we first delve into the problematic consequences of viral pandemics followed by an introduction on SARS-CoV-2 taxonomical classification. Then, we elaborate on the immunology of COVID-19. Common antiviral therapies and their related limitations are described and finally, the potential applicability of chitin and chitosan to fight this overwhelming viral pandemic is addressed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Chitin / Chitosan / Pandemics / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal: Int J Biol Macromol Year: 2021 Document Type: Article Affiliation country: J.ijbiomac.2021.04.157

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Chitin / Chitosan / Pandemics / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal: Int J Biol Macromol Year: 2021 Document Type: Article Affiliation country: J.ijbiomac.2021.04.157