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Pulmonary fibrosis 4 months after COVID-19 is associated with severity of illness and blood leucocyte telomere length
Thorax ; 29:29, 2021.
Article in English | MEDLINE | ID: covidwho-1209856
ABSTRACT
The risk factors for development of fibrotic-like radiographic abnormalities after severe COVID-19 are incompletely described and the extent to which CT findings correlate with symptoms and physical function after hospitalisation remains unclear. At 4 months after hospitalisation, fibrotic-like patterns were more common in those who underwent mechanical ventilation (72%) than in those who did not (20%). We demonstrate that severity of initial illness, duration of mechanical ventilation, lactate dehydrogenase on admission and leucocyte telomere length are independent risk factors for fibrotic-like radiographic abnormalities. These fibrotic-like changes correlate with lung function, cough and measures of frailty, but not with dyspnoea.

Full text: Available Collection: Databases of international organizations Database: MEDLINE Type of study: Risk factors Language: English Journal: Thorax Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: MEDLINE Type of study: Risk factors Language: English Journal: Thorax Year: 2021 Document Type: Article