Afferent and Efferent Neuro-Ophthalmic Complications of Coronavirus Disease 19.
J Neuroophthalmol
; 41(2): 154-165, 2021 06 01.
Article
in English
| MEDLINE | ID: covidwho-1517959
ABSTRACT
PURPOSE:
To provide a summary of the neuro-ophthalmic manifestations of coronavirus disease 19 (COVID-19) documented in the literature thus far.METHODS:
The PubMed and Google Scholar databases were searched using the keywords Neuro-Ophthalmology, COVID-19, SARS-CoV-2, and coronavirus. A manual search through reference lists of relevant articles was also performed. RESULTS/CONCLUSIONS:
The literature on COVID-associated neuro-ophthalmic disease continues to grow. Afferent neuro-ophthalmic complications associated with COVID-19 include optic neuritis, papillophlebitis, papilledema, visual disturbance associated with posterior reversible encephalopathy syndrome, and vision loss caused by stroke. Efferent neuro-ophthalmic complications associated with COVID-19 include cranial neuropathies, Miller Fisher syndrome, Adie's pupils, ocular myasthenia gravis, nystagmus and eye movement disorders. Proposed mechanisms of neurologic disease include immunologic upregulation, vasodilation and vascular permeability, endothelial dysfunction, coagulopathy, and direct viral neurotropism. When patients present to medical centers with new onset neuro-ophthalmic conditions during the pandemic, COVID-19 infection should be kept on the differential.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Optic Neuritis
/
Posterior Leukoencephalopathy Syndrome
/
Pandemics
/
SARS-CoV-2
/
COVID-19
Type of study:
Observational study
/
Reviews
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
J Neuroophthalmol
Journal subject:
Neurology
/
Ophthalmology
Year:
2021
Document Type:
Article
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