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Is coronavirus disease 2019 associated with indicators of long-term bladder dysfunction?
Welk, Blayne; Richard, Lucie; Braschi, Emmanuel; Averbeck, Marcio A.
  • Welk B; Department of Surgery, Epidemiology and Biostatistics, Western University, London, Canada.
  • Richard L; ICES Western, London, Canada.
  • Braschi E; ICES Western, London, Canada.
  • Averbeck MA; Department of Urology, Instituto Nacional de Rehabilitación Psicofísica del Sur, Mar del Plata, Argentina.
Neurourol Urodyn ; 40(5): 1200-1206, 2021 06.
Article in English | MEDLINE | ID: covidwho-1212770
ABSTRACT

OBJECTIVE:

Early reports have suggested that coronavirus disease 2019 (COVID-19) can present with significant urinary frequency and nocturia, and that these symptoms correlate with markers of inflammation in the urine. We evaluated surrogate markers of chronic urinary symptoms to determine if they were more frequent after COVID-19 infection.

METHODS:

Routinely collected data from the province of Ontario was used to conduct a matched, retrospective cohort study. We identified patients 66 years of age or older who had a positive COVID-19 test between February and May 2020 and survived at least 2 months after their diagnosis. We matched them to two similar patients who did not have a positive COVID-19 test during the same time period. We measured the frequency of urology consultation, cystoscopy, and new prescriptions for overactive bladder medications during a subsequent 3-month period. Proportional hazard models were adjusted for any baseline differences between the groups.

RESULTS:

We matched 5617 patients with COVID-19 to 11,225 people who did not have COVID-19. The groups were similar, aside from a higher proportion of patients having hypertension and diabetes in the CoVID-19 cohort. There was no significantly increased hazard of new receipt of overactive bladder medication (hazards ratio [HR] 1.04, p = 0.88), urology consultation (HR 1.40, p = 0.10), or cystoscopy (HR 1.14, p = 0.50) among patients who had COVID-19, compared to the matched cohort.

CONCLUSION:

Surrogate markers of potential bladder dysfunction were not significantly increased in the 2-5 months after COVID-19 infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Urinary Bladder, Overactive / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Aged / Female / Humans / Male Country/Region as subject: North America Language: English Journal: Neurourol Urodyn Year: 2021 Document Type: Article Affiliation country: Nau.24682

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Urinary Bladder, Overactive / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Aged / Female / Humans / Male Country/Region as subject: North America Language: English Journal: Neurourol Urodyn Year: 2021 Document Type: Article Affiliation country: Nau.24682