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Clinical characteristics and outcomes of hospitalized COVID-19 patients with COPD.
Turan, Onur; Arpinar Yigitbas, Burcu; Turan, Pakize Ayse; Mirici, Arzu.
  • Turan O; Chest Diseases Department, Izmir Katip Celebi University Atatürk Research and Training Hospital, Izmir, Turkey.
  • Arpinar Yigitbas B; Chest Diseases Department, Yedikule Hospital for Chest Disease and Thoracic Surgery, Istanbul, Turkey.
  • Turan PA; Chest Diseases Department, Menemen State Hospital, Izmir, Turkey.
  • Mirici A; Chest Diseases Department, Canakkale 18 Mart University, Canakkale, Turkey.
Expert Rev Respir Med ; 15(8): 1069-1076, 2021 08.
Article in English | MEDLINE | ID: covidwho-1214360
ABSTRACT

BACKGROUND:

Although COPD is not one of the most common comorbidities in COVID-19 patients, it can be more fatal in this group. This study aimed to investigate the characteristics and prognosis of COPD patients among the population with COVID-19. RESEARCH DESIGN AND

METHODS:

Patients diagnosed with positive PCR test were included in our multicentered, retrospective study. Patients with airway obstruction (previous spirometry) were included in 'COPD group'.

RESULTS:

The prevalence of COPD in COVID-19 patients was 4.96%(53/1069). There was a significant difference between COPD and non-COPD COVID-19 patients in terms of gender, mean age, presence of dyspnea, tachypnea, tachycardia, hypoxemia and presence of pneumonia. The mortality rate was 13.2% in COPD, 7% in non-COPD patients(p = 0.092). The significant predictors of mortality were higher age, lymphopenia (p < 0.001), hypoxemia (p = 0.028), high D-dimer level (p = 0.011), and presence of pneumonia (p = 0.043) in COVID-19 patients.

CONCLUSIONS:

Our research is one of the first studies investigating characteristics of COPD patients with COVID-19 in Turkey. Although COPD patients had some poor prognostic features, there was no statistical difference between overall survival rates of two groups. Age, status of oxygenization, serum D-dimer level, lymphocyte count and pneumonia were significantly associated parameters with mortality in COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / Pulmonary Disease, Chronic Obstructive / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Expert Rev Respir Med Year: 2021 Document Type: Article Affiliation country: 17476348.2021.1923484

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / Pulmonary Disease, Chronic Obstructive / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Expert Rev Respir Med Year: 2021 Document Type: Article Affiliation country: 17476348.2021.1923484