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Coronavirus infection in hip fractures (CHIP) study.
Mahmood, Aatif; Rashid, Fatima; Limb, Richard; Cash, Thomas; Nagy, Mathias Thomas; Zreik, Nasri; Reddy, Gautam; Jaly, Ibrahim; As-Sultany, Mohammed; Chan, Yuen Ting Carol; Wilson, Graeme; Harrison, W J.
  • Mahmood A; The Countess of Chester NHS Foundation Trust, Chester, UK.
  • Rashid F; The Countess of Chester NHS Foundation Trust, Chester, UK.
  • Limb R; Macclesfield District General Hospital, Macclesfield, UK.
  • Cash T; Mid Cheshire Hospitals NHS Foundation Trust, Crewe, UK.
  • Nagy MT; Wrightington, Wigan and Leigh NHS Foundation trust, Wigan, UK.
  • Zreik N; Liverpool University Hospitals Foundation Trust, Liverpool, UK.
  • Reddy G; Liverpool University Hospitals Foundation Trust, Liverpool, UK.
  • Jaly I; Southport and Ormskirk Hospital NHS Trust, Southport, UK.
  • As-Sultany M; Warrington and Halton Teaching Hospitals NHS Foundation Trust, Warrington, UK.
  • Chan YTC; St Helen and Knowsley Teaching Hospital NHS Trust, Whiston, UK.
  • Wilson G; Wirral University Teaching Hospital NHS Foundation Trust, Birkenhead, UK.
  • Harrison WJ; The Countess of Chester NHS Foundation Trust, Chester, UK.
Bone Joint J ; 103-B(4): 782-787, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-1215141
ABSTRACT

AIMS:

Despite the COVID-19 pandemic, incidence of hip fracture has not changed. Evidence has shown increased mortality rates associated with COVID-19 infection. However, little is known about the outcomes of COVID-19 negative patients in a pandemic environment. In addition, the impact of vitamin D levels on mortality in COVID-19 hip fracture patients has yet to be determined.

METHODS:

This multicentre observational study included 1,633 patients who sustained a hip fracture across nine hospital trusts in North West England. Data were collected for three months from March 2020 and for the same period in 2019. Patients were matched by Nottingham Hip Fracture Score (NHFS), hospital, and fracture type. We looked at the mortality outcomes of COVID-19 positive and COVID-19 negative patients sustaining a hip fracture. We also looked to see if vitamin D levels had an impact on mortality.

RESULTS:

The demographics of the 2019 and 2020 groups were similar, with a slight increase in proportion of male patients in the 2020 group. The 30-day mortality was 35.6% in COVID-19 positive patients and 7.8% in the COVID-19 negative patients. There was a potential association of decreasing vitamin D levels and increasing mortality rates for COVID-19 positive patients although our findings did not reach statistical significance.

CONCLUSION:

In 2020 there was a significant increase in 30-day mortality rates of patients who were COVID-19 positive but not of patients who were COVID-19 negative. Low levels of vitamin D may be associated with high mortality rates in COVID-19 positive patients. Cite this article Bone Joint J 2021;103-B(4)782-787.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vitamin D Deficiency / COVID-19 / Hip Fractures Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Bone Joint J Year: 2021 Document Type: Article Affiliation country: 0301-620x.103b.Bjj-2020-1862.R1

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vitamin D Deficiency / COVID-19 / Hip Fractures Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Bone Joint J Year: 2021 Document Type: Article Affiliation country: 0301-620x.103b.Bjj-2020-1862.R1