Depression and Anxiety Among Patients with Cancer During COVID-19 Pandemic: A Systematic Review and Meta-analysis.
J Gastrointest Cancer
; 52(2): 499-507, 2021 Jun.
Article
in English
| MEDLINE | ID: covidwho-1216261
ABSTRACT
BACKGROUND:
Investigations about the impact and consequences of the COVID-19 infection on the mental health of patients with chronic diseases and those with immunosuppressive conditions are growing. The current study aimed to systematically review and meta-analysis of studies that evaluated the level of depression and anxiety in cancer patients during the COVID-19 pandemic.METHODS:
The PubMed, Scopus and Web of Sciences databases were searched to retrieve potential studies from January 2020 to 3 January 2021. Summary data on frequency and mean of depression and anxiety were extracted. Random-effect meta-analysis was conducted to estimate overall prevalence, mean and standardized mean difference.RESULTS:
Thirty-four studies were included in the systematic review, of them 21 studies included in meta-analysis. Overall depression and anxiety were 0.37 (0.27, 0.47); I2 = 99.05%, P value < 0.001 and 0.38 (0.31, 0.46); I2 = 99.08%, P value < 0.001, respectively. Compared to controls, cancer patients had higher anxiety level [standard mean difference (SMD 0.25 (95% CI 0.08, 0.42)].CONCLUSION:
Overall, the findings of this study suggest that the prevalence of depression and anxiety among patients with cancer during the COVID-19 pandemic can reach considerable levels, although observed substantial heterogeneity should be considered when interpreting the results.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Anxiety
/
Depression
/
SARS-CoV-2
/
COVID-19
/
Neoplasms
Type of study:
Experimental Studies
/
Observational study
/
Randomized controlled trials
/
Reviews
/
Systematic review/Meta Analysis
Limits:
Humans
Language:
English
Journal:
J Gastrointest Cancer
Year:
2021
Document Type:
Article
Affiliation country:
S12029-021-00643-9
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