Association Between Statin Use Prior to Admission and Lower Coronavirus Disease 2019 (COVID-19) Severity in Patients With Cardiovascular Disease or Risk Factors.
Circ J
; 85(6): 939-943, 2021 05 25.
Article
in English
| MEDLINE | ID: covidwho-1216946
ABSTRACT
BACKGROUND:
Cardiovascular diseases and/or risk factors (CVDRF) have been reported as risk factors for severe coronavirus disease 2019 (COVID-19).MethodsâandâResults:
In total, we selected 693 patients with CVDRF from the CLAVIS-COVID database of 1,518 cases in Japan. The mean age was 68 years (35% females). Statin use was reported by 31% patients at admission. Statin users exhibited lower incidence of extracorporeal membrane oxygenation (ECMO) insertion (1.4% vs. 4.6%, odds ratio [OR] 0.295, P=0.037) and septic shock (1.4% vs. 6.5%, OR 0.205, P=0.004) despite having more comorbidities such as diabetes mellitus.CONCLUSIONS:
This study suggests the potential benefits of statins use against COVID-19.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Patient Admission
/
Cardiovascular Diseases
/
Hydroxymethylglutaryl-CoA Reductase Inhibitors
/
Dyslipidemias
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
English
Journal:
Circ J
Journal subject:
Vascular Diseases
/
Cardiology
Year:
2021
Document Type:
Article
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