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How we approach thrombosis risk in children with COVID-19 infection and MIS-C.
Sharathkumar, Anjali A; Faustino, E Vincent S; Takemoto, Clifford M.
  • Sharathkumar AA; Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Faustino EVS; Section of Pediatric Critical Care Medicine, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.
  • Takemoto CM; Division of Clinical Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Pediatr Blood Cancer ; 68(7): e29049, 2021 07.
Article in English | MEDLINE | ID: covidwho-1217408
ABSTRACT
Thrombosis within the microvasculature and medium to large vessels is a serious and common complication among critically ill individuals with coronavirus disease 2019 (COVID-19). While children are markedly less likely to develop severe disease than adults, they remain at risk for thrombosis during acute infection and with the post-acute inflammatory illness termed multisystem inflammatory syndrome in children. Significant knowledge deficits in understanding COVID-19-associated coagulopathy and thrombotic risk pose clinical challenges for pediatric providers who must incorporate expert opinion and personal experience to manage individual patients. We discuss clinical scenarios to provide framework for characterizing thrombosis risk and thromboprophylaxis in children with COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombosis / Systemic Inflammatory Response Syndrome / SARS-CoV-2 / COVID-19 / COVID-19 Drug Treatment / Anticoagulants Type of study: Case report / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Female / Humans / Male Language: English Journal: Pediatr Blood Cancer Journal subject: Hematology / Neoplasms / Pediatrics Year: 2021 Document Type: Article Affiliation country: Pbc.29049

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombosis / Systemic Inflammatory Response Syndrome / SARS-CoV-2 / COVID-19 / COVID-19 Drug Treatment / Anticoagulants Type of study: Case report / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Female / Humans / Male Language: English Journal: Pediatr Blood Cancer Journal subject: Hematology / Neoplasms / Pediatrics Year: 2021 Document Type: Article Affiliation country: Pbc.29049