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Application of an evidence-based, out-patient treatment strategy for COVID-19: Multidisciplinary medical practice principles to prevent severe disease.
Frohman, Elliot M; Villemarette-Pittman, Nicole R; Rodriguez, Adriana; Glanzman, Robert; Rugheimer, Sarah; Komogortsev, Oleg; Zamvil, Scott S; Cruz, Roberto Alejandro; Varkey, Thomas C; Frohman, Ashley N; Frohman, Audrey R; Parsons, Matthew S; Konkle, Emily Heckmann; Frohman, Teresa C.
  • Frohman EM; Laboratory of Neuroimmunology, Professor Lawrence Steinman, Stanford University School of Medicine, United States of America. Electronic address: Elliot.frohman@utexas.edu.
  • Villemarette-Pittman NR; Department of Neurology, LSU Health Sciences Center New Orleans, Louisiana, United States of America. Electronic address: nville@lsuhsc.edu.
  • Rodriguez A; Department of Emergency Medicine, Cook Children's Medical Center, Ft. Worth, TX, United States of America.
  • Glanzman R; Clene Nanomedicine, Inc., Salt Lake City, UT 84121, United States of America. Electronic address: robert@clene.com.
  • Rugheimer S; Department of Physics, University Oxford, Oxford OX1 3PU, UK. Electronic address: sarah.rugheimer@physics.ox.ac.uk.
  • Komogortsev O; Department of Computer Sciences, Texas State University, San Marcos, TX, United States of America. Electronic address: ok11@txstate.edu.
  • Zamvil SS; Department of Neurology and Program in Immunology, University of California San Francisco, San Francisco, CA, United States of America. Electronic address: zamvil@ucsf.neuroimmunol.org.
  • Cruz RA; Department of Neurology, Doctor's Health at Renaissance Health Neurology Institute, United States of America; Department of Neurology, University of Texas Rio Grande Valley School of Medicine, United States of America. Electronic address: roberto.cruzsaldana@austin.utexas.edu.
  • Varkey TC; Dell Medical School, University of Texas at Austin, United States of America. Electronic address: tvarkey@utexas.edu.
  • Frohman AN; The Frohman Foundation, Austin, TX, United States of America. Electronic address: ash21375019@yahoo.com.
  • Frohman AR; The Frohman Foundation, Austin, TX, United States of America. Electronic address: frohman.audrey@yahoo.com.
  • Parsons MS; Division of Microbiology and Immunology, Yerkes National Primate Research Center, United States of America; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, United States of America. Electronic address: matthew.s.parsons@emory.edu.
  • Konkle EH; The Frohman Foundation, Austin, TX, United States of America. Electronic address: emily@digitalknowledge.net.
  • Frohman TC; Laboratory of Neuroimmunology, Professor Lawrence Steinman, Stanford University School of Medicine, United States of America. Electronic address: teresafrohmanCOVID@gmail.com.
J Neurol Sci ; 426: 117463, 2021 Jul 15.
Article in English | MEDLINE | ID: covidwho-1220928
ABSTRACT
The COVID-19 pandemic has devastated individuals, families, and institutions throughout the world. Despite the breakneck speed of vaccine development, the human population remains at risk of further devastation. The decision to not become vaccinated, the protracted rollout of available vaccine, vaccine failure, mutational forms of the SARS virus, which may exhibit mounting resistance to our molecular strike at only one form of the viral family, and the rapid ability of the virus(es) to hitch a ride on our global transportation systems, means that we are will likely continue to confront an invisible, yet devastating foe. The enemy targets one of our human physiology's most important and vulnerable life-preserving body tissues, our broncho-alveolar gas exchange apparatus. Notwithstanding the fear and the fury of this microbe's potential to raise existential questions across the entire spectrum of human endeavor, the application of an early treatment intervention initiative may represent a crucial tool in our defensive strategy. This strategy is driven by evidence-based medical practice principles, those not likely to become antiquated, given the molecular diversity and mutational evolution of this very clever "world traveler".
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Neurol Sci Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Neurol Sci Year: 2021 Document Type: Article