Obesity, COVID-19 and innate immunometabolism.
Br J Nutr
; 125(6): 628-632, 2021 03 28.
Article
in English
| MEDLINE | ID: covidwho-1221095
ABSTRACT
As COVID-19 continues to spread worldwide, severe disease and mortality have been observed in obese patients. We discuss how obesity and obesity-associated factors such as 'meta-flammation', dietary fat intake and paradoxical suppression of the innate immune response within the pulmonary compartment may be crucial determinants in the host response to a novel viral pathogen. Modulation of immune cell bioenergetics and metabolic potential plays a central role in the innate immune response to infection, and as we strive to combat this new global health threat, immunometabolism of the innate immune system warrants attention.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
/
Immune System
/
Obesity
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Br J Nutr
Year:
2021
Document Type:
Article
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