Your browser doesn't support javascript.
COVID-19 in the tonsillectomised population.
Capriotti, Vincenzo; Mattioli, Francesco; Guida, Francesco; Marcuzzo, Alberto Vito; Lo Manto, Alfredo; Martone, Andrea; Molinari, Giulia; Fabbris, Cristoforo; Menegaldo, Anna; Calvanese, Leonardo; Latini, Gino; Cingolani, Cristina; Gradoni, Paolo; Boscolo Nata, Francesca; De Sisti, Clelia; Selle, Vittorio; Leone, Giordano; Indelicato, Pietro; Pilolli, Francesco; Mevio, Niccolò; Roncoroni, Luca; Papi, Simona; Meschiari, Marianna; Tominz, Riccardo; D'Ascanio, Luca; Dragonetti, Alberto; Torelli, Lucio; Trenti, Loris; Spinato, Giacomo; Boscolo-Rizzo, Paolo; Bussi, Mario; Cossarizza, Andrea; Presutti, Livio; Tirelli, Giancarlo.
  • Capriotti V; Otorhinolaryngology-Head and Neck Surgery Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
  • Mattioli F; Otorhinolaryngology-Head and Neck Surgery Department, University Hospital of Modena, Italy.
  • Guida F; Otorhinolaryngology-Head and Neck Surgery Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
  • Marcuzzo AV; Otorhinolaryngology-Head and Neck Surgery Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
  • Lo Manto A; Otorhinolaryngology-Head and Neck Surgery Department, University Hospital of Modena, Italy.
  • Martone A; Otorhinolaryngology-Head and Neck Surgery Department, University Hospital of Modena, Italy.
  • Molinari G; Otorhinolaryngology-Head and Neck Surgery Department, University Hospital of Modena, Italy.
  • Fabbris C; ENT Clinic and Regional Center for Head and Neck Cancer, University of Padova Faculty of Medicine and Surgery, Department of Neurosciences, Treviso Regional Hospital, Treviso, Italy.
  • Menegaldo A; ENT Clinic and Regional Center for Head and Neck Cancer, University of Padova Faculty of Medicine and Surgery, Department of Neurosciences, Treviso Regional Hospital, Treviso, Italy.
  • Calvanese L; ENT Clinic and Regional Center for Head and Neck Cancer, University of Padova Faculty of Medicine and Surgery, Department of Neurosciences, Treviso Regional Hospital, Treviso, Italy.
  • Latini G; Institute of Otorhinolaryngology, Department of Head and Neck Surgery, Santa Croce Hospital AORMN, Fano (PU), Italy.
  • Cingolani C; Institute of Otorhinolaryngology, Department of Head and Neck Surgery, Santa Croce Hospital AORMN, Fano (PU), Italy.
  • Gradoni P; Institute of Otorhinolaryngology, Department of Head and Neck Surgery, Santa Croce Hospital AORMN, Fano (PU), Italy.
  • Boscolo Nata F; Otorhinolaryngology Unit, Monselice Hospital, Ospedali Riuniti Padova Sud "Madre Teresa di Calcutta", Monselice (PD), Italy.
  • De Sisti C; Hygiene and Public Health Unit, Department of Prevention, Hospital of Chioggia, AULSS 3 Serenissima, Chioggia (VE), Italy.
  • Selle V; Hygiene and Public Health Unit, Department of Prevention, Hospital of Chioggia, AULSS 3 Serenissima, Chioggia (VE), Italy.
  • Leone G; Department of Otorhinolaryngology, San Raffaele Hospital, Milano, Italy.
  • Indelicato P; Department of Otorhinolaryngology, San Raffaele Hospital, Milano, Italy.
  • Pilolli F; Department of Otorhinolaryngology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
  • Mevio N; Department of Otorhinolaryngology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
  • Roncoroni L; Department of Otorhinolaryngology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
  • Papi S; Department of Surgery and Clinical Specialties, University of Modena and Reggio Emilia, Modena, Italy.
  • Meschiari M; Department of Infectious Diseases, Azienda Ospedaliero-Universitaria Policlinico of Modena, University of Modena and Reggio Emilia Faculty of Medicine and Surgery, Modena, Italy.
  • Tominz R; Department of Prevention, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
  • D'Ascanio L; Institute of Otorhinolaryngology, Department of Head and Neck Surgery, Santa Croce Hospital AORMN, Fano (PU), Italy.
  • Dragonetti A; Department of Otorhinolaryngology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
  • Torelli L; Department of Medical, Surgical and Health Sciences, University of Trieste, Italy.
  • Trenti L; Department of General and Digestive Surgery, Colorectal Unit, Bellvitge University Hospital, Barcelona, Spain.
  • Spinato G; ENT Clinic and Regional Center for Head and Neck Cancer, University of Padova Faculty of Medicine and Surgery, Department of Neurosciences, Treviso Regional Hospital, Treviso, Italy.
  • Boscolo-Rizzo P; ENT Clinic and Regional Center for Head and Neck Cancer, University of Padova Faculty of Medicine and Surgery, Department of Neurosciences, Treviso Regional Hospital, Treviso, Italy.
  • Bussi M; Hygiene and Public Health Unit, Department of Prevention, Hospital of Chioggia, AULSS 3 Serenissima, Chioggia (VE), Italy.
  • Cossarizza A; Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Presutti L; Otorhinolaryngology-Head and Neck Surgery Department, University Hospital of Modena, Italy.
  • Tirelli G; Otorhinolaryngology-Head and Neck Surgery Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
Acta Otorhinolaryngol Ital ; 41(3): 197-205, 2021 Jun.
Article in English | MEDLINE | ID: covidwho-1222316
ABSTRACT

OBJECTIVE:

Interactions between SARS-CoV-2 and pharyngeal associated lymphoid tissue are thought to influence the manifestations of COVID-19. We aimed to determine whether a previous history of tonsillectomy, as a surrogate indicator of a dysfunctional pharyngeal associated lymphoid tissue, could predict the presentation and course of COVID-19.

METHODS:

Multicentric cross-sectional observational study involving seven hospitals in Northern and Central Italy. Data on the clinical course and signs and symptoms of the infection were collected from 779 adults who tested positive for SARS-CoV-2, and analysed in relation to previous tonsillectomy, together with demographic and anamnestic data.

RESULTS:

Patients with previous tonsillectomy showed a greater risk of fever, temperature higher than 39°C, chills and malaise. No significant differences in hospital admissions were found.

CONCLUSIONS:

A previous history of tonsillectomy, as a surrogate indicator of immunological dysfunction of the pharyngeal associated lymphoid tissue, could predict a more intense systemic manifestation of COVID-19. These results could provide a simple clinical marker to discriminate suspected carriers and to delineate more precise prognostic models.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Palatine Tonsil / Tonsillectomy / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Acta Otorhinolaryngol Ital Year: 2021 Document Type: Article Affiliation country: 0392-100x-n1436

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Palatine Tonsil / Tonsillectomy / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Acta Otorhinolaryngol Ital Year: 2021 Document Type: Article Affiliation country: 0392-100x-n1436