Does COVID-19 infection influence patients' performance during IVF-ET cycle?: an observational study.
Gynecol Endocrinol
; 37(10): 895-897, 2021 Oct.
Article
in English
| MEDLINE | ID: covidwho-1223203
ABSTRACT
OBJECTIVE:
No information exists in the literature regarding the effect of coronavirus disease 19 (COVID-19) infection on subsequent in vitro fertilization (IVF) cycle attempt. We, therefore, aim to assess the influence of COVID-19 infection on IVF treatments.DESIGN:
An observational study.SETTING:
A tertiary, university-affiliated medical center. PATIENTS ANDMETHODS:
All consecutive couples undergoing ovarian stimulation (OS) for IVF, before and after recovering from COVID-19 infection, and reached the ovum pick-up (OPU) stage. The stimulation characteristics and embryological variables of couples undergoing IVF treatments after recovering from COVID-19 infection were assessed and compared to their IVF cycles prior to COVID-19 infection. MAIN OUTCOMEMEASURES:
Stimulation characteristics and embryological variables.RESULTS:
Nine couples (seven with the female partner infection and two with the male partner) resumed IVF treatment 8-92 d after recovering from the COVID-19 infection (negative polymerase chain reaction [PCR]). No in-between cycles differences were observed in OS and embryological variables between the cycles before and after recovering from the COVID-19 infection, except for a significantly lower proportion of top-quality embryos.CONCLUSIONS:
COVID-19 infection did not affect patients' performance or ovarian reserve in their immediate subsequent IVF cycle, except for a reduced proportion of top-quality embryos (TQEs). We therefore suggest, to postpone IVF treatment for a least 3 months (duration of folliculogenesis and spermatogenesis) after recovering from COVID-19 infection, aiming to recruit healthy gametes that were not exposed to COVID-19 infection during their development.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Fertilization in Vitro
/
Treatment Outcome
/
Embryo Transfer
/
SARS-CoV-2
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Gynecol Endocrinol
Journal subject:
Endocrinology
/
Gynecology
Year:
2021
Document Type:
Article
Affiliation country:
09513590.2021.1918080
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