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An Agitated Patient With COVID-19 Infection and Early-onset Alzheimer Disease.
Sykora, Daniel; Stonnington, Cynthia M; Jain, Neeta.
  • Sykora D; Mayo Clinic Alix School of Medicine.
  • Stonnington CM; Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ.
  • Jain N; Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ.
Alzheimer Dis Assoc Disord ; 36(1): 83-84, 2022.
Article in English | MEDLINE | ID: covidwho-1223417
ABSTRACT
Encephalopathy, delirium, and agitation are documented symptoms of coronavirus disease (COVID-19) infection, but research into the management of agitation in the setting of COVID-19 and pre-existing neuropsychiatric disease is ongoing. We present a 55-year-old male patient with early-onset Alzheimer disease and deteriorating mental and functional status who presented to our institution with agitation and persistent COVID-19 positivity on polymerase chain reaction testing. His agitation was improved through pharmacologic optimization including the avoidance of benzodiazepines and initiation of clonidine and prazosin, which temporally coincided with the resolution of his nearly 2-month long COVID-19 positivity.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Alzheimer Disease / COVID-19 Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Humans / Male / Middle aged Language: English Journal: Alzheimer Dis Assoc Disord Journal subject: Neurology / Psychiatry Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Alzheimer Disease / COVID-19 Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Humans / Male / Middle aged Language: English Journal: Alzheimer Dis Assoc Disord Journal subject: Neurology / Psychiatry Year: 2022 Document Type: Article