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Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective.
Mazur, Marta; Dus-Ilnicka, Irena; Jedlinski, Maciej; Ndokaj, Artnora; Janiszewska-Olszowska, Joanna; Ardan, Roman; Radwan-Oczko, Malgorzata; Guerra, Fabrizio; Luzzi, Valeria; Vozza, Iole; Marasca, Roberto; Ottolenghi, Livia; Polimeni, Antonella.
  • Mazur M; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
  • Dus-Ilnicka I; Department of Oral Pathology, Wroclaw Medical University, ul. Krakowska 26, 52-425 Wroclaw, Poland.
  • Jedlinski M; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
  • Ndokaj A; Department of Interdisciplinary Dentistry, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.
  • Janiszewska-Olszowska J; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
  • Ardan R; Department of Interdisciplinary Dentistry, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.
  • Radwan-Oczko M; Department of Economic Sciences, Koszalin University of Technology, 75-343 Koszalin, Poland.
  • Guerra F; Department of Oral Pathology, Wroclaw Medical University, ul. Krakowska 26, 52-425 Wroclaw, Poland.
  • Luzzi V; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
  • Vozza I; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
  • Marasca R; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
  • Ottolenghi L; Paediatric Dentistry Unit, Head and Neck Integrated Department, AOU Policlinico Umberto I of Rome, Viale Regina Elena 287/b, 00161 Rome, Italy.
  • Polimeni A; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
Int J Environ Res Public Health ; 18(9)2021 May 07.
Article in English | MEDLINE | ID: covidwho-1224003
ABSTRACT
(1)

Background:

Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) emerged in Wuhan, China, in late 2019. The development of effective and safe vaccines against SARS-CoV-2 has been extremely fast. The list of orofacial adverse effects of BNT162b2 and mRNA-1273 vaccines based on the clinical trials are reported to be rare. The aim of this study was to investigate the facial and oral manifestations of COVID-19 vaccination using a survey-based study. (2)

Methods:

The questionnaire was developed using Google Forms and sent anonymously to a total of 700 subjects (medical personnel) in Poland, Italy, and other EU countries. (3)

Results:

223 people answered the questionnaire, mainly vaccinated with BNT162b2. Only 3.1% and 5.4% experienced oral and facial symptoms, respectively. General diseases presence and age have significant influence on the probability of oral symptoms occurrence after the second dose. Facial symptoms are correlated with general disease; autoimmune pathologies and age, at first and second dose, respectively. Gender, smoking and regular medication intake have significant influence on the probability of taking an absence day. Gender, age, and smoking have a significant influence on the duration of symptoms after second dose. (4)

Conclusions:

Based on the results of this preliminary survey, there is no observed significant correlation between vaccine administration for COVID-19 and facial and oral manifestations.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid / Vaccines Limits: Humans Country/Region as subject: Asia / Europa Language: English Year: 2021 Document Type: Article Affiliation country: Ijerph18094965

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid / Vaccines Limits: Humans Country/Region as subject: Asia / Europa Language: English Year: 2021 Document Type: Article Affiliation country: Ijerph18094965