Skin manifestations as potential symptoms of diffuse vascular injury in critical COVID-19 patients.
J Cutan Pathol
; 48(10): 1266-1276, 2021 Oct.
Article
in English
| MEDLINE | ID: covidwho-1225664
ABSTRACT
As a respiratory viral infection caused by a novel coronavirus, COVID-19 became rapidly pandemic within a few months. Despite the wide range of manifestations and organ involvement in COVID-19 patients, the exact pathogenesis of severe and fatal types of COVID-19 and causes involved with the individual base of the disease is not yet understood. Several studies have reported clinical, laboratory, and histopathological data in favor of vascular injury in multiple organs of critically ill patients with COVID-19 as a result of hyperactive immune response, inflammation, and cytokine storm. Also, both clinical and histopathological evidence points to such vascular involvements in the skin. Given the ease of clinical examinations and skin biopsy and the lower risks of transmission of COVID-19 to healthcare workers, the present review article was conducted to investigate the vascular skin manifestations of COVID-19 patients clinically and/or histopathologically as helpful clues for better understanding the pathogenesis and predicting the prognosis of the disease, especially in severe cases.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Skin
/
Peripheral Vascular Diseases
/
COVID-19
Type of study:
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
J Cutan Pathol
Year:
2021
Document Type:
Article
Affiliation country:
Cup.14059
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