Life-Threatening Diffuse Alveolar Hemorrhage as an Initial Presentation of Microscopic Polyangiitis: COVID-19 as a Likely Culprit.
Cureus
; 13(4): e14403, 2021 Apr 10.
Article
in English
| MEDLINE | ID: covidwho-1227169
ABSTRACT
Microscopic polyangiitis (MPA) is a systemic small vessel vasculitis but it is rare to see life-threatening diffuse alveolar hemorrhage (DAH) in MPA as an initial presentation. MPA more commonly presents with renal involvement and develops pulmonary manifestations later in the disease course. Our patient is a 77-year-old female with a recent history of recovered COVID-19 infection who presented with sudden onset fever, dyspnea, and hemoptysis for three days. She was diagnosed with MPA because of the new-onset DAH, a strongly positive myeloperoxidase (MPO) antibody, and the low likelihood of another etiology. The patient was treated with pulse-dose steroids and plasmapheresis while being on mechanical ventilation. This case highlights the importance of the prompt recognition of DAH as an initial presentation of MPA and illustrates the possible role of COVID-19 in inciting autoimmune conditions.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Case report
/
Etiology study
/
Prognostic study
Language:
English
Journal:
Cureus
Year:
2021
Document Type:
Article
Affiliation country:
Cureus.14403
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