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Macrophage Activation in COVID-19 Patients in Intensive Care Unit.
Labro, Guylaine; Jandeaux, Louise Marie; Rusu, Andreea; Virot, Edouard; Pointurier, Valentin; Pinto, Luis; Mathien, Cyrille; Debliquis, Agathe; Harzallah, Ines; Mootien, Joy; Drenou, Bernard; Kuteifan, Khaldoun.
  • Labro G; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
  • Jandeaux LM; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
  • Rusu A; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
  • Virot E; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
  • Pointurier V; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
  • Pinto L; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
  • Mathien C; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
  • Debliquis A; Departement d'Hematologie, Groupe Hospitalier de la region Mulhouse Sud Alsace, Mulhouse, France.
  • Harzallah I; Departement d'Hematologie, Groupe Hospitalier de la region Mulhouse Sud Alsace, Mulhouse, France.
  • Mootien J; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
  • Drenou B; Departement d'Hematologie, Groupe Hospitalier de la region Mulhouse Sud Alsace, Mulhouse, France.
  • Kuteifan K; Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
J Med Cases ; 11(7): 211-214, 2020 Jul.
Article in English | MEDLINE | ID: covidwho-1227204
ABSTRACT
We report six cases of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, admitted to intensive care unit (ICU), for whom bone marrow aspirate revealed hemophagocytosis. We compared their clinical presentation and laboratory findings to those that can be encountered during a hemophagocytic lymphohistiocytosis. These observations might evoke a macrophage activation mechanism different from the one encountered in the hemophagocytic lymphohistiocytosis (HLH).
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Observational study / Prognostic study Language: English Journal: J Med Cases Year: 2020 Document Type: Article Affiliation country: Jmc3520

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Observational study / Prognostic study Language: English Journal: J Med Cases Year: 2020 Document Type: Article Affiliation country: Jmc3520