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COVID-19 Pneumonia or Hypereosinophilic Syndrome?
Serin, Istemi; Ulusoy, Avni; Onar, Mediha Irem; Dogu, Mehmet Hilmi.
  • Serin I; Department of Hematology, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, Turkey.
  • Ulusoy A; Department of Internal Medicine, University of Health Sciences, Bagcilar Training and Research Hospital, Bagcilar, Istanbul, Turkey.
  • Onar MI; Department of Internal Medicine, University of Health Sciences, Bagcilar Training and Research Hospital, Bagcilar, Istanbul, Turkey.
  • Dogu MH; Deparment of Internal Medicine and Hematology, Liv Hospital ULUS, Istanbul, Turkey.
J Med Cases ; 11(12): 400-402, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-1227212
ABSTRACT
Hypereosinophilic syndromes (HESs) are a group of disorders characterized by pathological proliferation of eosinophils. Diagnostic criteria include eosinophil count of 1,500/mm3 or higher, presence of organ involvement and exclusion of other causes of eosinophilia for at least 6 months. A 69-year-old male patient was referred to the pandemic clinic with a preliminary diagnosis of coronavirus disease 2019 (COVID-19) with fever and dyspnea. Computed tomography (CT) was compatible with COVID-19, nasopharyngeal swab polymerase chain reaction (PCR) was negative for two times. He had 20,000/mm3 eosinophilia and retrospective examinations showed that he have had eosinophilia for more than 1 year. Platelet-derived growth factor receptor alpha (PDGFRα) resulted positively. After starting parenteral methylprednisolone with a dose of 1 mg/kg, he was discharged with oral maintenance therapy. In outpatient follow-up, it was observed that eosinophilic pneumonia completely regressed. HES may occur with multiple system and organ involvement and findings. In the differential diagnosis of patients presenting with heart failure, pulmonary involvement and eosinophilia, HES must definitely be considered.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Cohort study / Diagnostic study / Observational study / Prognostic study Language: English Journal: J Med Cases Year: 2020 Document Type: Article Affiliation country: Jmc3587

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Cohort study / Diagnostic study / Observational study / Prognostic study Language: English Journal: J Med Cases Year: 2020 Document Type: Article Affiliation country: Jmc3587