Authors' reply: the biologic importance of the vitamin D binding protein polymorphism in pediatric COVID-19 patients.
Eur J Pediatr
; 180(8): 2709-2710, 2021 Aug.
Article
in English
| MEDLINE | ID: covidwho-1227845
ABSTRACT
What is Known? ⢠Vitamin D has multiple roles in the immune system that can modulate the body reaction to an infection ⢠Vitamin D binding protein (DBP) is the key transport protein which, along with albumin, binds over 99% of the circulating vitamin D metabolites What is New? ⢠Lower 25 OH vitamin D levels were associated with higher inflammation markers, suggesting an important role of vitamin D in the clinical course of COVID-19 in children and adolescents probably by regulating the systemic inflammatory response ⢠Further studies are warranted to investigate the possible causal association of DBP levels and polymorphism with vitamin D status (total and bioavailable vitamin D) in COVID-19 patients.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Biological Products
/
COVID-19
Type of study:
Prognostic study
Limits:
Adolescent
/
Child
/
Humans
Language:
English
Journal:
Eur J Pediatr
Year:
2021
Document Type:
Article
Affiliation country:
S00431-021-04109-9
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