Influence of COVID-19 pandemic on quality of life in patients with epilepsy - Follow-up study.
Epilepsy Behav
; 121(Pt A): 108026, 2021 08.
Article
in English
| MEDLINE | ID: covidwho-1228173
ABSTRACT
OBJECTIVE:
To perform a follow-up study of the quality of life in patients with epilepsy in the era of the COVID-19 crisis.METHODS:
Two months before the first case of the COVID-19 in Serbia, we obtained the Serbian Version of Quality of Life Inventory for Epilepsy 31 (SVQOLIE-31) and Neurological Disorders Depression Inventory for Epilepsy scores (SVNDDI-E) for another study. We retested the same patients one year after in COVID-19 pandemic. In addition to SVQOLIE-31, and SVNDDI-E we used a generic questionnaire compiled from items related to the COVID-19.RESULTS:
We retested 97 out of 118 patients (82.2%) for the follow-up analysis. The average age was 36.1⯱â¯12.2 (range 18-69), and 49 were women (50.5%). The median duration of epilepsy was 13â¯years (range 1.5-48). The structural etiology of epilepsy was noted in 41 (42.3%), unknown etiology in 41 (42.3%), and genetic etiology in 15 (15.4%) patients. Fewer patients (27.8%) experienced at least one seizure three months before follow-up testing when compared to patients who experienced at least one seizure three months in initial testing (36.0%) (pâ¯=â¯0.15). All patients reported full compliance with anti-seizure medication in the follow-up. The SVQOLIE-31 score during the COVID-19 pandemic visit (64.5⯱â¯14.6) was significantly lower than the SVQOLIE-31 score before the pandemic (pâ¯<â¯0.001). The SVNDDI-E score during the COVID-19 pandemic (10.5⯱â¯3.5) was significantly higher than the SVNDDI-E score before it (pâ¯<â¯0.001). Multiple linear regression analyses revealed fear of seizures, and fear of a reduction in household income, significantly associated with SVQOLIE-31 and SVNDDI-E overall score. These variables accounted for 66% and 27% of the variance of SVQOLIE-31 and SVNDDI-E overall score.SIGNIFICANCE:
Lower quality of life, higher prevalence of depression, healthcare availability issues, and perceived fears during pandemic all suggest COVID-19 has negatively impacted lives of patients with epilepsy.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Epilepsy
/
COVID-19
Type of study:
Cohort study
/
Etiology study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Adult
/
Female
/
Humans
/
Middle aged
/
Young adult
Country/Region as subject:
Europa
Language:
English
Journal:
Epilepsy Behav
Journal subject:
Behavioral Sciences
/
Neurology
Year:
2021
Document Type:
Article
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