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COVID-19 vaccine-associated immune thrombosis and thrombocytopenia (VITT): Diagnostic and therapeutic recommendations for a new syndrome.
Franchini, Massimo; Liumbruno, Giancarlo Maria; Pezzo, Mario.
  • Franchini M; Department of Hematology and Transfusion Medicine, Carlo Poma Hospital, Mantova, Italy.
  • Liumbruno GM; Department of Hematology and Transfusion Medicine, Carlo Poma Hospital, Mantova, Italy.
  • Pezzo M; Department of Hematology and Transfusion Medicine, Carlo Poma Hospital, Mantova, Italy.
Eur J Haematol ; 107(2): 173-180, 2021 Aug.
Article in English | MEDLINE | ID: covidwho-1228750
ABSTRACT
Very rare cases of thrombosis associated with thrombocytopenia have occurred following the vaccination with AstraZeneca COVID-19 vaccine. The aim of this concise review is to summarize the current knowledge on the epidemiologic and pathogenic mechanisms of this syndrome named vaccine-associated immune thrombosis and thrombocytopenia (VITT). A practical patient management section will also be dealt with using information available from national and international scientific societies as well as expert panels. A literature search on the VITT syndrome was carried out in PubMed using appropriate MeSH headings. Overall, 40 VITT cases have been reported. Continuous pharmacovigilance monitoring is needed to collect more data on the real incidence and the pathogenesis of VITT syndrome. Such information will also help us to optimize the management this rare but often clinically severe thrombotic condition associated with COVID-19 vaccination.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombocytopenia / Thrombosis / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Reviews Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Eur J Haematol Journal subject: Hematology Year: 2021 Document Type: Article Affiliation country: Ejh.13665

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombocytopenia / Thrombosis / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Reviews Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Eur J Haematol Journal subject: Hematology Year: 2021 Document Type: Article Affiliation country: Ejh.13665