Does mRNA SARS-CoV-2 vaccine influence patients' performance during IVF-ET cycle?
Reprod Biol Endocrinol
; 19(1): 69, 2021 May 13.
Article
in English
| MEDLINE | ID: covidwho-1228997
ABSTRACT
OBJECTIVE:
No information exists in the literature regarding the effect of mRNA SARS-CoV-2 vaccine on subsequent IVF cycle attempt. We therefore aim to assess the influence of mRNA SARS-CoV-2 vaccine on IVF treatments.DESIGN:
An observational study.SETTING:
A tertiary, university-affiliated medical center. PATIENTS ANDMETHODS:
All couples undergoing consecutive ovarian stimulation cycles for IVF before and after receiving mRNA SARS-CoV-2 vaccine, and reached the ovum pick-up (OPU) stage. The stimulation characteristics and embryological variables of couples undergoing IVF treatments after receiving mRNA SARS-CoV-2 vaccine were assessed and compared to their IVF cycles prior to vaccination. MAIN OUTCOMEMEASURES:
Stimulation characteristics and embryological variables.RESULTS:
Thirty-six couples resumed IVF treatment 7-85 days after receiving mRNA SARS-CoV-2 vaccine. No in-between cycles differences were observed in ovarian stimulation and embryological variables before and after receiving mRNA SARS-CoV-2 vaccination.CONCLUSIONS:
mRNA SARS-CoV-2 vaccine did not affect patients' performance or ovarian reserve in their immediate subsequent IVF cycle. Future larger studies with longer follow-up will be needed to validate our observations.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Fertilization in Vitro
/
Embryo Transfer
/
COVID-19 Vaccines
/
SARS-CoV-2
/
COVID-19
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Adult
/
Female
/
Humans
/
Male
/
Pregnancy
Language:
English
Journal:
Reprod Biol Endocrinol
Journal subject:
Endocrinology
/
Reproductive Medicine
Year:
2021
Document Type:
Article
Affiliation country:
S12958-021-00757-6
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