Metal Complexes as Antiviral Agents for SARS-CoV-2.
Chembiochem
; 22(16): 2600-2607, 2021 08 17.
Article
in English
| MEDLINE | ID: covidwho-1231848
ABSTRACT
The severe acute respiratory syndrome - coronavirus 2 (SARS-CoV-2), the infectious agent responsible for COVID-19 - has caused more than 2.5 million deaths worldwide and triggered a global pandemic. Even with successful vaccines being delivered, there is an urgent need for novel treatments to combat SARS-CoV-2, and other emerging viral diseases. While several organic small molecule drug candidates are in development, some effort has also been devoted towards the application of metal complexes as potential antiviral agents against SARS-CoV-2. Herein, the metal complexes that have been reported to show antiviral activity against SARS-CoV-2 or one of its target proteins are described and their proposed mechanisms of action are discussed.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Coordination Complexes
/
SARS-CoV-2
Topics:
Vaccines
Language:
English
Journal:
Chembiochem
Journal subject:
Biochemistry
Year:
2021
Document Type:
Article
Affiliation country:
Cbic.202100186
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