Converging global crises are forcing the rapid adoption of disruptive changes in drug discovery.
Drug Discov Today
; 26(11): 2489-2495, 2021 11.
Article
in English
| MEDLINE | ID: covidwho-1233409
ABSTRACT
Spiralling research costs combined with urgent pressures from the Coronavirus 2019 (COVID-19) pandemic and the consequences of climate disruption are forcing changes in drug discovery. Increasing the predictive power of in vitro human assays and using them earlier in discovery would refocus resources on more successful research strategies and reduce animal studies. Increasing laboratory automation enables effective social distancing for researchers, while allowing integrated data capture from remote laboratory networks. Such disruptive changes would not only enable more cost-effective drug discovery, but could also reduce the overall carbon footprint of discovering new drugs.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Climate Change
/
Artificial Intelligence
/
Drug Discovery
/
Disruptive Technology
/
COVID-19
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Drug Discov Today
Journal subject:
Pharmacology
/
Drug Therapy
Year:
2021
Document Type:
Article
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