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Position paper on the preparation of immune plasma to be used in the treatment of patients with COVID-19.
Accorsi, Patrizia; Berti, Pierluigi; de Angelis, Vincenzo; De Silvestro, Giustina; Mascaretti, Luca; Ostuni, Angelo.
  • Accorsi P; Department of Haematology, Transfusion Medicine and Biotechnologies, Ospedale Civile, Pescara, Italy.
  • Berti P; Immunohaematology and Transfusion Medicine, "Umberto Parini" Hospital, Aosta, Italy.
  • de Angelis V; Transfusion Medicine Department, Azienda Sanitaria Universitaria "Friuli Centrale", Udine, Italy. Electronic address: vincenzo.deangelis@asufc.sanita.fvg.it.
  • De Silvestro G; Blood Transfusion Service, University Hospital of Padua, Padua, Italy.
  • Mascaretti L; Transfusion Medicine Department, Azienda Sanitaria Universitaria "Giuliano Isontina", Trieste, Italy.
  • Ostuni A; Transfusional Medicine Unit, University-Hospital Policlinico, Bari, Italy.
Transfus Apher Sci ; 59(4): 102817, 2020 Aug.
Article in English | MEDLINE | ID: covidwho-1235989
ABSTRACT
Passive immunotherapy with plasma derived from patients convalescent from SARS-CoV-2 infection can be a promising approach in the treatment of COVID-19 patients. It is important that Blood Establishments are prepared to satisfy requests for immune plasma by defining the requirements applicable to plasma donors and the standards for preparation, qualification, storage, distribution and control of use of the product. This position paper is aimed to give recommendations on biological characteristics of a plasma preparation from convalescent donors and to support the evaluation of this therapeutic approach in more rigorous investigations.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Immunization, Passive / Coronavirus Infections / Betacoronavirus Type of study: Experimental Studies / Prognostic study Limits: Humans Language: English Journal: Transfus Apher Sci Journal subject: Hematology Year: 2020 Document Type: Article Affiliation country: J.transci.2020.102817

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Immunization, Passive / Coronavirus Infections / Betacoronavirus Type of study: Experimental Studies / Prognostic study Limits: Humans Language: English Journal: Transfus Apher Sci Journal subject: Hematology Year: 2020 Document Type: Article Affiliation country: J.transci.2020.102817