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Immediate high-dose intravenous immunoglobulins followed by direct thrombin-inhibitor treatment is crucial for survival in Sars-Covid-19-adenoviral vector vaccine-induced immune thrombotic thrombocytopenia VITT with cerebral sinus venous and portal vein thrombosis.
Graf, Tilmann; Thiele, Thomas; Klingebiel, Randolf; Greinacher, Andreas; Schäbitz, Wolf-Rüdiger; Greeve, Isabell.
  • Graf T; Department of Neurology, Evangelisches Klinikum Bethel, OWL University Hospital, Bielefeld University, Bielefeld-Bethel Campus, Bielefeld, Germany.
  • Thiele T; Department of Transfusion Medicine, Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.
  • Klingebiel R; Department of Neuroradiology, Evangelisches Klinikum Bethel, OWL University Hospital, Bielefeld University, Bielefeld-Bethel Campus, Bielefeld, Germany.
  • Greinacher A; Department of Transfusion Medicine, Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.
  • Schäbitz WR; Department of Neurology, Evangelisches Klinikum Bethel, OWL University Hospital, Bielefeld University, Bielefeld-Bethel Campus, Bielefeld, Germany.
  • Greeve I; Department of Neurology, Evangelisches Klinikum Bethel, OWL University Hospital, Bielefeld University, Bielefeld-Bethel Campus, Bielefeld, Germany. isabell.greeve@evkb.de.
J Neurol ; 268(12): 4483-4485, 2021 Dec.
Article in English | MEDLINE | ID: covidwho-1237498
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombocytopenia / Thrombosis / Antithrombins / Immunoglobulins, Intravenous / COVID-19 Vaccines / COVID-19 Type of study: Case report / Prognostic study Topics: Vaccines Limits: Adult / Humans / Male Language: English Journal: J Neurol Year: 2021 Document Type: Article Affiliation country: S00415-021-10599-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombocytopenia / Thrombosis / Antithrombins / Immunoglobulins, Intravenous / COVID-19 Vaccines / COVID-19 Type of study: Case report / Prognostic study Topics: Vaccines Limits: Adult / Humans / Male Language: English Journal: J Neurol Year: 2021 Document Type: Article Affiliation country: S00415-021-10599-2