A case report of acquired hemophilia following COVID-19 vaccine.
J Thromb Haemost
; 19(6): 1515-1518, 2021 06.
Article
in English
| MEDLINE | ID: covidwho-1238450
ABSTRACT
Acquires hemophilia A (AHA) is rare bleeding condition commonly associated with malignancy, autoimmune disease, or pregnancy. We report a case of a 69-year-old gentleman who developed bleeding symptoms after receiving COVID-19 vaccine. Laboratory testing showed isolated prolongation of the activated partial thromboplastin time, and normal von Willebrand factor. Further testing confirmed the presence of factor VIII inhibitor. To date, no cases of AHA have been reported after exposure to COVID-19 vaccine. There have been two cases of AHA following seasonal flu and H1N1 vaccination, as well as two cases of AHA following COVID-19 infection. We present a summary of these cases and review of literature of autoimmune reactions following vaccination.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Influenza A Virus, H1N1 Subtype
/
COVID-19
/
Hemophilia A
Type of study:
Case report
/
Diagnostic study
Topics:
Vaccines
Limits:
Aged
/
Female
/
Humans
/
Male
/
Pregnancy
Language:
English
Journal:
J Thromb Haemost
Journal subject:
Hematology
Year:
2021
Document Type:
Article
Affiliation country:
Jth.15291
Similar
MEDLINE
...
LILACS
LIS