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Defeating Paediatric Tuberculous Meningitis: Applying the WHO "Defeating Meningitis by 2030: Global Roadmap".
Basu Roy, Robindra; Bakeera-Kitaka, Sabrina; Chabala, Chishala; Gibb, Diana M; Huynh, Julie; Mujuru, Hilda; Sankhyan, Naveen; Seddon, James A; Sharma, Suvasini; Singh, Varinder; Wobudeya, Eric; Anderson, Suzanne T.
  • Basu Roy R; Clinical Research Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
  • Bakeera-Kitaka S; MRC Clinical Trials Unit at UCL, 90 High Holborn, Holborn, London WC1V 6LJ, UK.
  • Chabala C; MUJHU Research Collaboration, Kampala, Uganda.
  • Gibb DM; School of Medicine & University Teaching Hospital (UTH), University of Zambia, Lusaka, Zambia.
  • Huynh J; MRC Clinical Trials Unit at UCL, 90 High Holborn, Holborn, London WC1V 6LJ, UK.
  • Mujuru H; Oxford University Clinical Research Unit, Centre for Tropical Medicine, Hospital for Tropical Diseases, 764 Vo Van Kiet, District 5, Ho Chi Minh City, Vietnam.
  • Sankhyan N; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Oxford University, Oxford OX3 7LG, UK.
  • Seddon JA; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.
  • Sharma S; Post Graduate Institute of Education and Medical Research (PGI), Chandigarh 160017, India.
  • Singh V; Department of Infectious Diseases, Imperial College London, Norfolk Place, London W2 1PG, UK.
  • Wobudeya E; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town 8000, South Africa.
  • Anderson ST; Department of Pediatrics, Lady Hardinge Medical College and Assoc Kalawati Saran Children's Hospital (Hospital-LHH), New Delhi 110001, India.
Microorganisms ; 9(4)2021 Apr 16.
Article in English | MEDLINE | ID: covidwho-1238917
ABSTRACT
Children affected by tuberculous meningitis (TBM), as well as their families, have needs that lie at the intersections between the tuberculosis and meningitis clinical, research, and policy spheres. There is therefore a substantial risk that these needs are not fully met by either programme. In this narrative review article, we use the World Health Organization (WHO) "Defeating Meningitis by 2030 global roadmap" as a starting point to consider key goals and activities to specifically defeat TBM in children. We apply the five pillars outlined in the roadmap to describe how this approach can be adapted to serve children affected by TBM. The pillars are (i) prevention; (ii) diagnosis and treatment; (iii) surveillance; (iv) support and care for people affected by meningitis; and (v) advocacy and engagement. We conclude by calling for greater integration between meningitis and TB programmes at WHO and at national levels.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study / Reviews Language: English Year: 2021 Document Type: Article Affiliation country: Microorganisms9040857

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study / Reviews Language: English Year: 2021 Document Type: Article Affiliation country: Microorganisms9040857