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High-performance antiviral nano-systems as a shield to inhibit viral infections: SARS-CoV-2 as a model case study.
Sadique, Mohd Abubakar; Yadav, Shalu; Ranjan, Pushpesh; Verma, Sarika; Salammal, Shabi Thankaraj; Khan, Mohd Akram; Kaushik, Ajeet; Khan, Raju.
  • Sadique MA; Microfluidics & MEMS Centre, CSIR - Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, India. khan.raju@gmail.com.
  • Yadav S; Microfluidics & MEMS Centre, CSIR - Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, India. khan.raju@gmail.com and Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Ranjan P; Microfluidics & MEMS Centre, CSIR - Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, India. khan.raju@gmail.com and Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Verma S; Microfluidics & MEMS Centre, CSIR - Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, India. khan.raju@gmail.com and Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Salammal ST; Microfluidics & MEMS Centre, CSIR - Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, India. khan.raju@gmail.com and Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Khan MA; Microfluidics & MEMS Centre, CSIR - Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, India. khan.raju@gmail.com and Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Kaushik A; NanoBioTech Laboratory, Health Systems Engineering, Department of Natural Sciences, Florida Polytechnic University, Lakeland, Florida 33805, USA.
  • Khan R; Microfluidics & MEMS Centre, CSIR - Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal 462026, India. khan.raju@gmail.com and Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
J Mater Chem B ; 9(23): 4620-4642, 2021 06 16.
Article in English | MEDLINE | ID: covidwho-1240778
Semantic information from SemMedBD (by NLM)
1. SARS coronavirus CAUSES Respiration Disorders
Subject
SARS coronavirus
Predicate
CAUSES
Object
Respiration Disorders
2. SARS coronavirus CAUSES Respiration Disorders
Subject
SARS coronavirus
Predicate
CAUSES
Object
Respiration Disorders
ABSTRACT
Despite significant accomplishments in developing efficient rapid sensing systems and nano-therapeutics of higher efficacy, the recent coronavirus disease (COVID-19) pandemic is not under control successfully because the severe acute respiratory syndrome virus (SARS-CoV-2, original and mutated) transmits easily from human to -human and causes life-threatening respiratory disorders. Thus, it has become crucial to avoid this transmission through precautions and keep premises hygienic using high-performance anti-viral nanomaterials to trap and eradicate SARS-CoV-2. Such an antiviral nano-system has successfully demonstrated useful significant contribution in COVID-19 pandemic/endemic management effectively. However, their projection with potential sustainable prospects still requires considerable attention and efforts. With this aim, the presented review highlights various severe life-threatening viral infections and the role of multi-functional anti-viral nanostructures with manipulative properties investigated as an efficient precative shielding agent against viral infection progression. The salient features of such various nanostructures, antiviral mechanisms, and high impact multi-dimensional roles are systematically discussed in this review. Additionally, the challenges associated with the projection of alternative approaches also support the demand and significance of this selected scientific topic. The outcomes of this review will certainly be useful to motivate scholars of various expertise who are planning future research in the field of investigating sustainable and affordable high-performance nano-systems of desired antiviral performance to manage not only COVID-19 infection but other targeted viral infections as well.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Antiviral Agents / Coated Materials, Biocompatible / Nanostructures / COVID-19 / Models, Biological Subject: Antiviral Agents / Coated Materials, Biocompatible / Nanostructures / COVID-19 / Models, Biological Language: English Journal: J Mater Chem B Clinical aspect: Therapy Year: 2021

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Antiviral Agents / Coated Materials, Biocompatible / Nanostructures / COVID-19 / Models, Biological Subject: Antiviral Agents / Coated Materials, Biocompatible / Nanostructures / COVID-19 / Models, Biological Language: English Journal: J Mater Chem B Clinical aspect: Therapy Year: 2021
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