Coronavirus disease 2019 and kidney injury.
Curr Opin Nephrol Hypertens
; 30(4): 444-449, 2021 07 01.
Article
in English
| MEDLINE | ID: covidwho-1240971
ABSTRACT
PURPOSE OF REVIEW In this paper, we seek to review coronavirus disease 2019 (COVID-19) associated kidney injury with a focus on what is known about pathophysiology. RECENT FINDINGS:
Kidney injury is a common complication of SARS-CoV-2 infection and is associated with increased morbidity and mortality. Acute tubular necrosis and glomerular injury are two common findings. Direct viral effect, endothelial dysfunction, and podocyte and tubular epithelial injury have been described. COVID-19-related glomerular injury may also be associated with high-risk APOL1 genotype.SUMMARY:
Data on COVID-19 renal involvement have suggested novel mechanisms of kidney injury that need to be further elucidated. More data are needed on renal involvement in milder disease, renal-specific therapeutic interventions, and long-term sequelae.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Acute Kidney Injury
/
COVID-19
Type of study:
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Curr Opin Nephrol Hypertens
Journal subject:
Vascular Diseases
/
Nephrology
Year:
2021
Document Type:
Article
Affiliation country:
MNH.0000000000000718
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