Your browser doesn't support javascript.
The importance of early detection of ENT symptoms in mild-to-moderate COVID-19.
Spinato, Giacomo; Costantini, Giulio; Fabbris, Cristoforo; Menegaldo, Anna; Mularoni, Francesca; Gaudioso, Piergiorgio; Mantovani, Monica; Borsetto, Daniele; Vijendren, Ananth; Da Mosto, Maria Cristina; Boscolo-Rizzo, Paolo.
  • Spinato G; Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy.
  • Costantini G; Department of Surgery, Oncology and Gastroenterology, Section of Oncology and Immunology, University of Padova, Padova, Italy.
  • Fabbris C; Psychology Department, University of Milano-Bicocca, Milano, Italy.
  • Menegaldo A; Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy.
  • Mularoni F; Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy.
  • Gaudioso P; Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy.
  • Mantovani M; Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy.
  • Borsetto D; Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy.
  • Vijendren A; Guy's and St Thomas' Hospitals, London, United Kingdom.
  • Da Mosto MC; ENT Department, Lister Hospital, Stevenage, United Kingdom.
  • Boscolo-Rizzo P; Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy.
Acta Otorhinolaryngol Ital ; 41(2): 101-107, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-1241350
Semantic information from SemMedBD (by NLM)
1. Pharyngeal structure LOCATION_OF Nasal symptom
Subject
Pharyngeal structure
Predicate
LOCATION_OF
Object
Nasal symptom
2. Entire ear LOCATION_OF Early Diagnosis
Subject
Entire ear
Predicate
LOCATION_OF
Object
Early Diagnosis
3. Early Diagnosis DIAGNOSES COVID-19
Subject
Early Diagnosis
Predicate
DIAGNOSES
Object
COVID-19
4. 2019 novel coronavirus CAUSES COVID-19
Subject
2019 novel coronavirus
Predicate
CAUSES
Object
COVID-19
5. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
6. Influenza-like symptoms NEG_ASSOCIATED_WITH COVID-19
Subject
Influenza-like symptoms
Predicate
NEG_ASSOCIATED_WITH
Object
COVID-19
7. Entire ear PART_OF Patients
Subject
Entire ear
Predicate
PART_OF
Object
Patients
8. Pharyngeal structure LOCATION_OF Nasal symptom
Subject
Pharyngeal structure
Predicate
LOCATION_OF
Object
Nasal symptom
9. Entire ear LOCATION_OF Early Diagnosis
Subject
Entire ear
Predicate
LOCATION_OF
Object
Early Diagnosis
10. Early Diagnosis DIAGNOSES COVID-19
Subject
Early Diagnosis
Predicate
DIAGNOSES
Object
COVID-19
11. 2019 novel coronavirus CAUSES COVID-19
Subject
2019 novel coronavirus
Predicate
CAUSES
Object
COVID-19
12. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
13. Influenza-like symptoms NEG_ASSOCIATED_WITH COVID-19
Subject
Influenza-like symptoms
Predicate
NEG_ASSOCIATED_WITH
Object
COVID-19
14. Entire ear PART_OF Patients
Subject
Entire ear
Predicate
PART_OF
Object
Patients
ABSTRACT

OBJECTIVES:

Patients with coronavirus disease-19 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may present with a wide range of symptoms. In this paper, a detailed characterisation of mild-to-moderate ear, nose nd throat (ENT) symptoms is presented with the aim of recognising the disease early to help reduce further spread and progression.

METHODS:

A total of 230 cases testing positive for SARS-CoV-2 and 134 negative controls were recruited for a case-control analysis. Symptoms were analysed using the Acute Respiratory Tract Infections Questionnaire, while other symptoms were investigated by ad hoc questions.

RESULTS:

Among the study samples (n = 364), 149 were males and 215 were females with age ranging from 20 to 89 years (mean 52.3). Four main groups of symptoms were obtained influenza-like symptoms, ENT-symptoms, breathing issues and asthenia-related symptoms, representing 72%, 69%, 64% and 53% of overall referred clinical manifestations, respectively. ENT symptoms, breathing issues and influenza-like symptoms were associated with positivity to SARS-CoV-2, whereas asthenia-related symptoms did not show a significant association with SARS-CoV-2 infection after controlling for other symptoms, comorbidities and demographic characteristics.

CONCLUSIONS:

ENT symptoms are equally represented with influenza-like ones as presenting symptoms of COVID-19. Patients with ENT symptoms should be investigated for early identification and prevention of SARS-CoV-2 spread.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Otorhinolaryngologic Diseases / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials / Risk factors / Screening study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged / Young adult Language: English Journal: Acta Otorhinolaryngol Ital Year: 2021 Document Type: Article Affiliation country: 0392-100X-N1038

Full text: Available Collection: International databases Database: MEDLINE Main subject: Otorhinolaryngologic Diseases / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials / Risk factors / Screening study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged / Young adult Language: English Journal: Acta Otorhinolaryngol Ital Year: 2021 Document Type: Article Affiliation country: 0392-100X-N1038