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COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient.
Ordoñez, Nicolás Ariza; Sepulveda, Valeria Gomez; Vargas, Lina Patricia; Moreno, Julian Mauricio.
  • Ordoñez NA; Fundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia.
  • Sepulveda VG; Universidad del Rosario, Bogotá, Colombia.
  • Vargas LP; Fundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia.
  • Moreno JM; Universidad del Rosario, Bogotá, Colombia.
Rev Inst Med Trop Sao Paulo ; 63: e42, 2021.
Article in English | MEDLINE | ID: covidwho-1243899
ABSTRACT
Acute generalised exanthematous pustulosis (AGEP) is an unusual cutaneous reaction, most often related with a hypersensitivity reaction to commonly used drugs. It is characterized by an abrupt onset of a pustular rash within hours or days after drug exposure and usually resolves spontaneously within 1-2 weeks after drug discontinuation. Some cases associated with systemic involvement and shock have been reported. We present the case of a severe AGEP, manifesting in association with systemic involvement and haemodynamic instability resulting in shock and multiorgan dysfunction in an adult female patient diagnosed with COVID-19 infection. There were no identifiable associated drugs, and the patient was not initiated on antimalarial drugs. Our patient improved rapidly, both hemodynamically and dermatologically with no directed therapy.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Acute Generalized Exanthematous Pustulosis / COVID-19 / Antimalarials Type of study: Case report / Diagnostic study Limits: Adult / Female / Humans Language: English Journal: Rev Inst Med Trop Sao Paulo Year: 2021 Document Type: Article Affiliation country: S1678-9946202163042

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Acute Generalized Exanthematous Pustulosis / COVID-19 / Antimalarials Type of study: Case report / Diagnostic study Limits: Adult / Female / Humans Language: English Journal: Rev Inst Med Trop Sao Paulo Year: 2021 Document Type: Article Affiliation country: S1678-9946202163042