Assessment of hemagglutination activity of porcine <i>deltacoronavirus</i>.

Zhang, Yunfei; Han, Li; Xia, Lu; Yuan, Yixin; Hu, Hui

Assessment of hemagglutination activity of porcine deltacoronavirus.

Zhang, Yunfei; Han, Li; Xia, Lu; Yuan, Yixin; Hu, Hui.

Zhang Y; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Han L; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Xia L; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Yuan Y; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Hu H; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.

J Vet Sci ; 21(1): e12, 2020 Jan.

Article in English | MEDLINE | ID: covidwho-124741

ABSTRACT

ABSTRACT

Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes diarrhea in piglets. However, the biological characteristics of PDCoV are unclear. In this study, the hemagglutination (HA) abilities of two PDCoV strains (CH-01 and HNZK-04) were investigated. Our results showed that PDCoV has the ability to agglutinate rabbit erythrocytes after virion pretreatment with trypsin or neuraminidase. Additionally, the HA assay results showed a significant positive correlation with the infectious viral titer. Our results suggest that assessing the HA activity of PDCoV may be a useful diagnostic method for investigating and surveilling PDCoV infections.

Subject(s)

Coronavirus Infections/veterinary; Coronavirus/physiology; Hemagglutination; Swine Diseases/immunology; Animals; Coronavirus Infections/immunology; Coronavirus Infections/virology; Diarrhea/immunology; Diarrhea/veterinary; Diarrhea/virology; Erythrocytes/immunology; Neuraminidase/administration & dosage; Rabbits; Swine; Swine Diseases/virology; Trypsin/administration & dosage; Virion/drug effects

Keywords

Porcine deltacoronavirus; hemagglutination; neuraminidase; trypsin

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Swine Diseases / Coronavirus Infections / Coronavirus / Hemagglutination Limits: Animals Language: English Journal: J Vet Sci Journal subject: Veterinary Medicine Year: 2020 Document Type: Article Affiliation country: Jvs.2020.21.e12

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