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Properties of Ethnomedicinal Plants and Their Bioactive Compounds: Possible Use for COVID-19 Prevention and Treatment.
Shoaib, Ambreen; Azmi, Lubna; Shukla, Ila; Alqahtani, Saad S; Alsarra, Ibrahim A; Shakeel, Faiyaz.
  • Shoaib A; Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
  • Azmi L; Department of Pharmaceutical Chemistry, Hygia Institute of Pharmaceutical Education & Research, Lucknow, Uttar Pradesh, India.
  • Shukla I; Department of Pharmacology, Jivika College of Pharmacy, Lucknow, Uttar Pradesh, India.
  • Alqahtani SS; Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
  • Alsarra IA; Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
  • Shakeel F; Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Curr Pharm Des ; 27(13): 1579-1587, 2021.
Article in English | MEDLINE | ID: covidwho-1247737
ABSTRACT

BACKGROUND:

The coronavirus disease 2019 (COVID-19) pandemic has changed the global scenario. To date, there are no treatment or preventive options. The discovery of a new drug will take time. In addition, the new drug will have side effects, and the virus will gradually become resistant to it. Therefore, it is important to search for a drug with a natural origin.

OBJECTIVE:

In this review, we analyzed and summarized various ethnomedicinal plants and their bioactive compounds as a source of antiviral agents for COVID-19 prevention and treatment.

METHODS:

From the literature, we selected different natural compounds that can act as potential targets at low cost with broad-spectrum antiviral activity.

RESULTS:

Of the 200 Chinese herbal extracts tested for their possible role against SARS-CoV, Lycoris radiata, Artemisia annua, Pyrrosia lingua, and Lindera aggregate showed anti-SARS-CoV effects with the median effective concentration = 2.4-88.2 µg/mL.

CONCLUSION:

Ethnomedicinal herbs can be used as an alternative source of novel, promising antiviral agents that might directly or indirectly inhibit the COVID-19 progression.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Topics: Traditional medicine Limits: Humans Language: English Journal: Curr Pharm Des Journal subject: Pharmacy Year: 2021 Document Type: Article Affiliation country: 1381612826666201106092021

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Topics: Traditional medicine Limits: Humans Language: English Journal: Curr Pharm Des Journal subject: Pharmacy Year: 2021 Document Type: Article Affiliation country: 1381612826666201106092021