SARS-CoV-2 infection and cancer: Evidence for and against a role of SARS-CoV-2 in cancer onset.
Bioessays
; 43(8): e2000289, 2021 08.
Article
in English
| MEDLINE | ID: covidwho-1251911
ABSTRACT
Despite huge efforts towards understanding the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis, little is known about the long-term consequences of the disease. Here, we critically review existing literature about oncogenesis as a potential long-term effect of SARS-CoV-2 infection. Like other viral infections, SARS-CoV-2 may promote cancer onset by inhibiting tumor suppressor genes. We conclude that, although unlikely, such hypothesis cannot be excluded a priori and we delineate an experimental approach to address it. Also see the video abstract here https//youtu.be/TBUTDSLR7vY.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Virus Diseases
/
COVID-19
/
Neoplasms
Limits:
Humans
Language:
English
Journal:
Bioessays
Journal subject:
Biology
/
Molecular Biology
Year:
2021
Document Type:
Article
Affiliation country:
Bies.202000289
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