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COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide.
Sun, Qisi; Fathy, Ramie; McMahon, Devon E; Freeman, Esther E.
  • Sun Q; Department of Dermatology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.
  • Fathy R; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA.
  • McMahon DE; Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
  • Freeman EE; Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA. Electronic address: efreeman@mgh.harvard.edu.
Dermatol Clin ; 39(4): 653-673, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1252657
ABSTRACT
In 2021, we entered a new phase of the COVID-19 pandemic. As mass vaccinations are underway and more vaccines are approved, it is important to recognize cutaneous adverse events. We review the dermatologic manifestations of COVID-19 vaccines as reported in clinical trial data and summarize additional observational reports of skin reactions to COVID-19 vaccines. Early-onset local injection reactions were the most common cutaneous side effects observed in clinical trials; delayed injection reactions were the most common cutaneous side effect reported outside of clinical trials. Understanding the landscape of cutaneous manifestations to COVID-19 vaccines is key to providing appropriate vaccine guidance.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Registries / Adverse Drug Reaction Reporting Systems / Drug Eruptions / Drug-Related Side Effects and Adverse Reactions / COVID-19 Vaccines Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Dermatol Clin Year: 2021 Document Type: Article Affiliation country: J.det.2021.05.016

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Registries / Adverse Drug Reaction Reporting Systems / Drug Eruptions / Drug-Related Side Effects and Adverse Reactions / COVID-19 Vaccines Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Dermatol Clin Year: 2021 Document Type: Article Affiliation country: J.det.2021.05.016