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Oxford-AstraZeneca COVID-19 vaccine: need of a reasoned and effective vaccine campaign.
Vallée, A; Chan-Hew-Wai, A; Bonan, B; Lesprit, P; Parquin, F; Catherinot, É; Choucair, J; Billard, D; Amiel-Taieb, C; Camps, È; Cerf, C; Zucman, D; Fourn, E.
  • Vallée A; Department of Clinical Research and Innovation, Foch Hospital, Suresnes, France. Electronic address: alexandre.g.vallee@gmail.com.
  • Chan-Hew-Wai A; Hospital Pharmacy, Foch Hospital, Suresnes, France.
  • Bonan B; Hospital Pharmacy, Foch Hospital, Suresnes, France.
  • Lesprit P; Department of Hygiene and Infectious Disease, Foch Hospital, Suresnes, France.
  • Parquin F; Intensive Respiratory Care Department, Foch Hospital, Suresnes, France.
  • Catherinot É; Department of Pneumology, Foch Hospital, Suresnes, France.
  • Choucair J; Department of Pneumology, Foch Hospital, Suresnes, France.
  • Billard D; Department of Oncology, Foch Hospital, Suresnes, France.
  • Amiel-Taieb C; Department of Occupational Health, Foch Hospital, Suresnes, France.
  • Camps È; Hospital Pharmacy, Foch Hospital, Suresnes, France.
  • Cerf C; Department of Intensive Care, Foch Hospital, Suresnes, France.
  • Zucman D; Department of Internal Medicine, Réseau Ville Hôpital Val de Seine, Foch Hospital, Suresnes, France.
  • Fourn E; Department of Internal Medicine, Réseau Ville Hôpital Val de Seine, Foch Hospital, Suresnes, France.
Public Health ; 196: 135-137, 2021 Jul.
Article in English | MEDLINE | ID: covidwho-1253510
ABSTRACT

OBJECTIVES:

A strong COVID-19 vaccine campaign is needed to reach the herd immunity and reduce this pandemic infection. STUDY

DESIGN:

In the Foch Hospital, France, in February 2021, 451 healthcare workers were vaccinated by a first dose of AstraZeneca vaccine.

METHODS:

Adverse effects were reported to our pharmaco-vigilance circuit, by an online and anonymous questionnaire following the first weeks of the vaccinal campaign to healthcare workers.

RESULTS:

Two hundred seventy-four (60.8%) of them reported multiple adverse effects. Main adverse effects reported were feverish state/chills (65.7%), fatigue/physical discomfort (62.4%), arthralgia/muscle pain (61.0%) and fever (44.5%).

CONCLUSIONS:

On March 2021 many European countries suspended AstraZeneca vaccine for one week due to safety uncertainty. Thus, confidence in its efficacy is undermined. However, the benefit/risk balance is clearly in favor of vaccination.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: Public Health Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: Public Health Year: 2021 Document Type: Article