Low-Cost Optical Assays for Point-of-Care Diagnosis in Resource-Limited Settings.
ACS Sens
; 6(6): 2108-2124, 2021 06 25.
Article
in English
| MEDLINE | ID: covidwho-1253892
ABSTRACT
Readily deployable, low-cost point-of-care medical devices such as lateral flow assays (LFAs), microfluidic paper-based analytical devices (µPADs), and microfluidic thread-based analytical devices (µTADs) are urgently needed in resource-poor settings. Governed by the ASSURED criteria (affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and deliverability) set by the World Health Organization, these reliable platforms can screen a myriad of chemical and biological analytes including viruses, bacteria, proteins, electrolytes, and narcotics. The Ebola epidemic in 2014 and the ongoing pandemic of SARS-CoV-2 have exemplified the ever-increasing importance of timely diagnostics to limit the spread of diseases. This review provides a comprehensive survey of LFAs, µPADs, and µTADs that can be deployed in resource-limited settings. The subsequent commercialization of these technologies will benefit the public health, especially in areas where access to healthcare is limited.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Point-of-Care Systems
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
Language:
English
Journal:
ACS Sens
Year:
2021
Document Type:
Article
Affiliation country:
Acssensors.1c00669
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